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2-(Benzofuran-2-yl)propan-2-ol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

59302-96-4

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59302-96-4 Usage

Appearance

White crystalline solid

Melting point

101-103°C

Derivative

Benzofuran and isopropanol

Usage

Building block in the synthesis of pharmaceuticals and organic compounds

Biological activities

Potential as an antitumor agent

Potential use

Production of perfumes and flavorings due to aromatic properties

Check Digit Verification of cas no

The CAS Registry Mumber 59302-96-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,3,0 and 2 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 59302-96:
(7*5)+(6*9)+(5*3)+(4*0)+(3*2)+(2*9)+(1*6)=134
134 % 10 = 4
So 59302-96-4 is a valid CAS Registry Number.

59302-96-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(1-benzofuran-2-yl)propan-2-ol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:59302-96-4 SDS

59302-96-4Downstream Products

59302-96-4Relevant academic research and scientific papers

Dual Cobalt and Photoredox Catalysis Enabled Redox-Neutral Annulation of 2-Propynolphenols

Ding, Hai-Xin,He, Yong-Qin,Song, Xian-Rong,Tian, Wan-Fa,Wang, Mei,Xiao, Qiang,Zhou, Zhao-Zhao,Zhu, Yao

supporting information, p. 3372 - 3377 (2021/06/08)

A hydroxyl-assisted, organophotoredox/cobalt dual catalyzed annulation of 2-propynolphenols to form 2-hydroxymethyl-benzo[b]furans was developed by employing 1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene (4CzIPN) as photosensitizer and CoCl2/su

Facile synthesis of 2-substituted benzo[: B] furans and indoles by copper-catalyzed intramolecular cyclization of 2-alkynyl phenols and tosylanilines

Rong, Zhouting,Gao, Kexin,Zhou, Lei,Lin, Jianyuan,Qian, Guoying

, p. 17975 - 17978 (2019/06/24)

A catalytic amount of CuCl and Cs2CO3 was employed to synthesize a variety of 2-substituted benzo[b]furans and indoles by an intramolecular cyclization of 2-alkynyl phenols and tosylanilines. This protocol features mild conditions, h

Catalytic Carbonylative Double Cyclization of 2-(3-Hydroxy-1-yn-1-yl)phenols in Ionic Liquids Leading to Furobenzofuranone Derivatives

Mancuso, Raffaella,Miliè, Rossana,Palumbo Piccionello, Antonio,Olivieri, Diego,Della Ca, Nicola,Carfagna, Carla,Gabriele, Bartolo

, p. 7303 - 7311 (2019/06/17)

A catalytic carbonylative double cyclization method for the synthesis of furo[3,4-b]benzofuran-1(3H)-ones is reported. It is based on the reaction between readily available 2-(3-hydroxy-1-yn-1-yl)phenols, CO, and oxygen carried out in the presence of cata

One-pot synthesis of 2-substituted benzo[b]furans via Pd-tetraphosphine catalyzed coupling of 2-halophenols with alkynes

Zhou, Rong,Wang, Wei,Jiang, Zhi-Jie,Wang, Kun,Zheng, Xue-Li,Fu, Hai-Yan,Chen, Hua,Li, Rui-Xiang

supporting information, p. 6023 - 6026 (2014/05/20)

A catalyst composed of [Pd(η3-C3H 5)Cl]2 and N,N,N',N'-tetra(diphenylphosphinomethyl) pyridine-2,6-diamine (L) was found to be effective for one-pot synthesis of 2-substituted benzo[b]furans from 2-halophenols and alkynes. For 2-bromo-3-hydroxypyridine, the catalyst loading could be as low as 1 ppm and the turnover number (TON) was up to 870000. the Partner Organisations 2014.

Synthesis of 2-substituted benzofurans from o-iodophenols and terminal alkynes with a recyclable palladium catalyst supported on nano-sized carbon balls under copper- and ligand-free conditions

Yum, Eul Kgun,Yang, Ok-Kyung,Kim, Ji-Eun,Park, Hee Jung

, p. 2645 - 2649 (2013/10/22)

We have developed a one-step synthesis of benzofurans from o-iodophenol and various terminal alkynes, by using Pd catalyst supported on nano-sized carbon balls (NCB) under copper- and ligand free conditions. This recyclable catalyst could be reused more than 5 times in the same heteroannulation reaction. The results have demonstrated that diverse 2-substituted benzofurans with tolerant functional groups can be prepared simply and conveniently under these conditions.

Scope and mechanism of the (4+3) cycloaddition reaction of furfuryl cations

Winne, Johan M.,Catak, Saron,Waroquier, Michel,Van Speybroeck, Veronique

supporting information; experimental part, p. 11990 - 11993 (2012/02/14)

It all adds up: Furfuryl alcohols are revealed as direct reaction partners for a wide range of conjugated dienes in a (4+3) cycloaddition motif (see scheme). This novel Lewis acid promoted process gives straightforward access to various polycyclic skeletons containing a seven-membered ring. A plausible cationic stepwise mechanism was confirmed by DFT calculations. Copyright

A novel water-soluble m-TPPTC ligand: Steric and electronic features - Recent developments in Pd- and Rh-catalyzed C-C bond formations

Genin, Emilie,Amengual, Remi,Michelet, Veronique,Savignac, Monique,Jutand, Anny,Neuville, Luc,Genet, Jean-Pierre

, p. 1733 - 1741 (2007/10/03)

The steric and electronic features of the novel water-soluble phosphane m-TPPTC have been determined using NMR, IR and UV-VIS spectroscopic methods and compared to the well-known sulfonated analogue TPPTS. The higher basicity of m-TPPTC compared to TPPTS

Pd/C mediated synthesis of 2-substituted benzo[b]furans/nitrobenzo[b] furans in water

Pal, Manojit,Subramanian, Venkataraman,Yeleswarapu, Koteswar Rao

, p. 8221 - 8225 (2007/10/03)

An efficient synthesis of 2-alkyl/aryl substituted benzo[b]furans/nitrobenzo[b]furans in water has been accomplished via Pd/C catalyzed reaction of o-iodophenols with terminal alkynes in the presence of PPh3, CuI and prolinol. This method can t

Palladium-catalysed heteroannulation with acetylenic compounds: Synthesis of benzofurans

Kundu, Nitya G.,Pal, Manojit,Mahanty, Jyan S.,De, Mahuya

, p. 2815 - 2820 (2007/10/03)

A detailed study of the heteroannulation of 0-iodophenol with acetylenic substrates through palladiumcopper catalysis leading to the synthesis of the 2-substituted benzofurans 21-29 is reported. An acylic compound 30 has been isolated and proved to be an intermediate in the synthesis of the benzofurans. Some of the benzofurans have been transformed into biologically active compounds.

A short synthetic route to benzofurans. syntheses of naturally occurring euparin and related compounds

Sogawa, Akihiro,Tsukayama, Masao,Nozaki, Hiroshi,Nakayama, Mitsuru

, p. 101 - 111 (2007/10/02)

Euparin (4a) and related benzofurans (4b-e, g) were synthesized by conversion of the corresponding o-(3-hydroxy-3-methylbutynyl)phenyl tosylates (2) in the presence of base into the 2-(1-hydroxy-1-methylethyl)benzofurans (3), followed by dehydration in hi

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