59338-94-2

Upstream product

• 65-49-6 4-Aminosalicylic acid 
• 50-86-2 4-acetamidosalicylic acid 
• 55304-05-7 4-acetylamino-2-methoxy-benzoic acid 
• 115919-39-6 2-methoxy-4,5-dinitrobenzoic acid 
• 2597-56-0 4-nitro-o-anisic acid 
• 13120-77-9 2-methyl-5-nitroanisole 
• 59338-90-8 4-amino-2-methoxy-5-nitrobenzoic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 112885-60-6 4-Amino-N-(4-benzyl-morpholin-2-ylmethyl)-2-methoxy-5-nitro-benzamide 
• 59338-95-3 2-methoxy 4-acetylamino 5-amino benzoic acid 
• 59338-90-8 4-amino-2-methoxy-5-nitrobenzoic acid 

Relevant academic research and scientific papers

Aminobenzoic acid derivative and preparation method and application thereof

The invention relates to an aminobenzoic acid derivative and a preparation method and application thereof, and belongs to the field of medicinal chemistry, and the structural formula of the aminobenzoic acid derivative is shown in the specification, R is alkyl, substituted phenyl, heteroaromatic ring group or substituted styryl; R is alkyl; R is alkyl, substituted phenyl or benzyl; R is alkyl; R is guanidyl; and R is alkyl. The preparation method is simple and high in yield. Most compounds of the invention have good influenza virus neuraminidase inhibition activity.

N-(1'-Allypyrrolidinyl 2'-methyl) 2-methoxy 4,5-azimido benzamide and its pharmaceutically acceptable salts

The azimido benzamide of this invention and its pharmaceutically acceptable salts have an unusually and unexpectedly high therapeutic index and low toxicity in the treatment of emesis in mammals. Pharmacological testing demonstrated the superior efficacy of the compound of this invention over known, similar compounds.