59374-52-6

Upstream product

• 3453-00-7 diethyl benzoylmethylphosphonate 
• 67264-28-2 diethyl (2-amino-2-phenylethyl)phosphonate 
• 70-11-1 α-bromoacetophenone 
• 93671-72-8 dimethyl (β-chlorostyryl)phosphonate 
• 1233181-68-4 dimethyl (2-amino-2-phenyl)ethylphosphonate 
• 100-42-5 styrene 
• 88184-60-5 C₁₄H₂₀NO₅P 
• 152801-76-8 {2-[(Z)-Methoxyimino]-2-phenyl-ethyl}-phosphonic acid diethyl ester 
• 88184-66-1 C₁₀H₁₀BrNO₂ 

Relevant academic research and scientific papers

Method for preparing beta-chloroalkenyl phosphonyl derivatives

The invention discloses a method for preparing beta-chloroalkenyl phosphonyl derivatives. Alkyne is taken as an initiator, and raw materials are easy to obtain and wide in variety. The product obtained with the method has diversified types and wide applications, can be directly used and can be used for synthesizing organic insecticides and pesticides. Besides, the method comprises simple steps andis mild in reaction condition, high in yield of target products, small in pollution, simple in reaction operation and aftertreatment process and suitable for industrial production.

A β - hydroxyalkanephosphonic ester derivatives

The invention discloses a preparation method of beta-hydroxyphosphonate derivatives. The preparation method comprises that an arylethene derivative, a phosphorus reagent and manganese acetate are dissolved in a solvent and the solution undergoes a reactio

Potential GABAB receptor antagonists. IX: The synthesis of 3-amino-3-(4-chlorophenyl)propanoic acid, 2-amino-2-(4-chlorophenyl)ethylphosphonic acid and 2-amino-2-(4-chlorophenyl)ethanesulfonic acid

This paper describes the synthesis of 3-amino-3-(4-chlorophenyl)propanoic acid and the corresponding phosphonic and sulfonic acids, lower homologues of baclofen, phaclofen and saclofen respectively. The chlorinated acids were all weak specific antagonists of GABA at the GABAB receptor, with the sulfonic acid (pA2 4·0) being stronger than the phosphonic acid (pA2 3·8) and carboxylic acid (pA2 3·5).

Synthesis and properties of 2-amino-2-arylethylphosphonic acids and derivatives

2-Amino-2-arylethylphosphonic acids, 6a to 6q have been prepared from the corresponding 2-acetoxyimino-or 2-methoxy imino-2-arylethylphosphonates, 3 or 4, by hydrogenation using Raney-Ni as a catalyst, followed by hydrolysis with HCl. 3 and 4 were obtaine

ORGANIC PHOSPHORUS COMPOUNDS 105 SYNTHESIS AND PROPERTIES OF 2-AMINO-2-ARYLETHYLPHOSPHONIC ACIDS AND DERIVATIVES

2-Amino-2-arylethylphosphonic acids, 6a to 6q have been prepared from the corresponding 2-acetoxyimino- or 2-methoxyimino-2-aryl-ethylphosphonates, 3 or 4, by hydrogenation using Raney-Ni as a catalyst, followed by hydrolysis with HCl. 3 and 4 were obtain

ANIMATION REDUCTRICE DES β-CETOPHOSPHONATES: PREPARATION D'ACIDES AMINOALKYLPHOSPHONIQUES

Diethyl 2-oxo-alkylphosphonates undergo reductive amination in the presence of an amine and sodium cyanohydridoborate (NaBH3CN) in MeOH at Ph 7-7.5.Studies with a large variety of ketophosphonates show that the reaction rate is very sensitive to steric hi