594860-94-3

Upstream product

• 384340-05-0 2-azido-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanone 
• 102293-80-1 2-bromo-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethanone 
• 626-01-7 3-Iodoaniline 
• 457644-49-4 3-(3-{4-[(6-{[(2R)-2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]but-1-ynyl}phenyl)imidazolidine-2,4-dione 
• 594860-96-5 {[(3-{4-[(6-{[(2R)-2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]butyl}anilino)carbonyl]amino}acetic acid 
• 64-19-7 acetic acid 
• 208925-08-0 (2R)-hydroxy-2-(2,2-dimethyl-4H-1,3-benzodioxine-6-yl)-ethylamine 
• 457631-24-2 3-(3-{4-[(6-{[(2R)-2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]butyl}phenyl)imidazolidine-2,4-dione 
• 457635-26-6 3-(3-iodophenyl)imidazolidine-2,4-dione 
• 457635-17-5 ethyl N-{[(3-iodophenyl)amino]carbonyl}glycinate 

Relevant academic research and scientific papers

The discovery of long-acting saligenin β2 adrenergic receptor agonists incorporating hydantoin or uracil rings

A series of novel, potent and selective human β2 adrenoceptor agonists incorporating a hydantoin or a uracil ring on the right-hand side phenyl ring of (R)-salmeterol is presented. Hydantoin 12a had long duration of action in vitro on guinea pi

PHENETHANOLAMINE DERIVATIVES FOR TREATMENT OF RESPIRATORY DISEASES

The present invention relates to novel compounds of formula (I),to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.