59489-32-6

Usage

Uses

Used in Flavor and Fragrance Industry:
5-Chloro-2,3-dimethylpyrazine is used as a flavoring agent for its ability to impart a pungent, roasted, and nutty aroma to various products in the flavor and fragrance industry.
Used in Natural Aroma Sources:
5-chloro-2,3-diMethylpyrazine is found in natural sources such as roasted coffee, cocoa, and cooked meat, where it contributes to their characteristic smell and taste, enhancing the sensory experience of these food items.
Used in Anticancer Research:
5-Chloro-2,3-dimethylpyrazine is used as a potential anti-cancer agent in research settings, with studies showing its ability to inhibit the growth of certain cancer cells. Further research is necessary to understand its mechanism of action and explore its potential as a therapeutic agent in oncology.

Upstream product

• 57229-36-4 2,3-Dimethyl-5-hydroxypyrazine 
• 2302-39-8 4,5-dimethylimidazole 
• 67-66-3 chloroform 
• 65464-21-3 2,3-dimethyl-1,4-diazine N-oxide 
• 5910-89-4 2,3-dimethylpyrazine 

Downstream Products

• 57229-36-4 2,3-Dimethyl-5-hydroxypyrazine 
• 32493-79-1 5,6-Dichloro-2,3-dimethylpyrazine 
• 1252906-06-1 2,3-dimethyl-5-[(phenylmethyl)oxy]pyrazine 

Relevant academic research and scientific papers

NOVEL COMPOUNDS WITH A 3A-AZABICYCLO [4.1.0] HEPTANE CORE ACTING ON OREXIN RECEPTORS

This invention relates to azabicyclo[4.1.0]hept-4-yl derivatives and their use as pharmaceuticals.

3 -AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS

This invention relates to 3-azabicyclo[4.1.0] heptane derivatives (I) and their use as orexin receptor antagonists.

SPIRO CONDENSED PIPERIDNES AS MODULATORS OF MUSCARINIC RECEPTORS

The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Syntheses and Reactions of Some 2,3-Disubstituted Pyrazine Monoxides

The reactions of 2,3-dimethyl- (4), 2,3-diphenyl- (6), and 2-methyl-3-phenyl-pyrazine monoxides (8 and 9) with phosphoryl chloride and acetic anhydride resulted in giving monochloro- and monoacetoxy-pyrazines in almost all cases.However, the reaction of 6 with acetic anhydride afforded exceptionally a diacetoxydihydropyrazine.These products were converted further to hydroxy or dichloro derivatives.

Reactions of Halogenomethanes in the Vapor Phase. Part 4. The Reactions of Imidazoles with Chloroform at 550 deg C, and a Comparison with their Liquid-phase Reactions with Trichloroacetate Ion or Hexachloroacetone and Base

1-Unsubstituted imidazoles and chloroform at 550 deg C in a flow system give mainly 5-chloropyrimidines, together with 4-chloropyrimidines and chloropyrazines.The effects of methyl substituents on the ratio of products is considered.The liquid-phase reactions of 2-methyl- and 2,4,5-trimethyl-imidazole under conditions in which dichlorocarbene is said to be formed in basic or neutral conditions were studied, and compared with the gas-phase reactions with chloroform.