57229-36-4Relevant academic research and scientific papers
Regioselective synthesis of trialkylpyrazines via nickel-catalyzed Negishi cross-coupling of pyrazine triflate
Pitchaiah, Arigala,Hwang, Intaek,Hwang, Jin-Soo,Kim, Hyungrok,Lee, Kee-In
experimental part, p. 1631 - 1636 (2012/06/30)
A regioselective synthesis of trialkylpyrazines via nickel-catalyzed cross-coupling reaction of pyrazine triflate is reported. The 5-substituted 2,3-dimethylpyrazine derivatives including trail pheromone components of the ant Eutetramorium mocquerysi have been successfully synthesized in good yields by nickel-catalyzed Negishi cross-coupling reactions of pyrazine triflate mediated by alkyl and arylzinc halides. Georg Thieme Verlag Stuttgart · New York.
3 -AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS
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Page/Page column 71, (2010/11/05)
This invention relates to 3-azabicyclo[4.1.0] heptane derivatives (I) and their use as orexin receptor antagonists.
At-hydroxyamide-containing heterocycles. Part 7. Preparation and photochemical behavior of 1-benzyloxy-2(1H)-pyrazinones
Ohkanda, Junko,Kumasaka, Toshihiko,Takasu, Aki,Hasegawa, Tadashi,Katoh, Akira
, p. 883 - 889 (2007/10/03)
Synthesis of 1-benzyloxy-2(1H)-pyrazinones having substituents at C-5 and C-6 positions and their photochemical behavior have been studied. Upon irradiation 1-benzyloxy-2(1H)-pyrazmones underwent N-O bond cleavage in high quantum yields. The rearrangement of the benzyioxy group to C-3 position of the ring and [2+2] cycloaddition were also observed.
Syntheses and Reactions of Some 2,3-Disubstituted Pyrazine Monoxides
Watahiki, Hiroko,Tsutsui, Mayumi,Akita, Yasuo,Watanabe, Tokuhiro,Kurihara, Teruo
, p. 465 - 473 (2007/10/02)
The reactions of 2,3-dimethyl- (4), 2,3-diphenyl- (6), and 2-methyl-3-phenyl-pyrazine monoxides (8 and 9) with phosphoryl chloride and acetic anhydride resulted in giving monochloro- and monoacetoxy-pyrazines in almost all cases.However, the reaction of 6 with acetic anhydride afforded exceptionally a diacetoxydihydropyrazine.These products were converted further to hydroxy or dichloro derivatives.
