59489-72-4

Basic information

• Product Name: PyrazinaMine, 5-(4-chlorophenyl)
• Synonyms: PyrazinaMine, 5-(4-chlorophenyl);5-(4-Chlorophenyl)pyrazin-2-aMine
• CAS NO: 59489-72-4
• Molecular Formula: C₁₀H₈ClN₃
• Molecular Weight: 205.64362
• EINECS: -0
• Mol File: 59489-72-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: PyrazinaMine, 5-(4-chlorophenyl)(CAS DataBase Reference)
• NIST Chemistry Reference: PyrazinaMine, 5-(4-chlorophenyl)(59489-72-4)
• EPA Substance Registry System: PyrazinaMine, 5-(4-chlorophenyl)(59489-72-4)

Safety Data

• Hazardous Substances Data: 59489-72-4(Hazardous Substances Data)

Upstream product

• 59489-71-3 5-amino-2-bromopyrazine 
• 1679-18-1 4-Chlorophenylboronic acid 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 274251-56-8 boronic acid 4-chlorophenyl monoester 

Downstream Products

• 69816-70-2 1-(2-chloro-benzoyl)-3-[5-(4-chloro-phenyl)-pyrazin-2-yl]-urea 
• 690266-90-1 2-(4-chloro-phenyl)-5-iodo-pyrazine 
• 59489-55-3 1-[5-(4-chloro-phenyl)-pyrazin-2-yl]-3-(2,6-dichloro-benzoyl)-urea 

Relevant articles and documents

Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds

Alkyne compounds having MCH-receptor antagonistic activity, which are useful for preparing pharmaceutical compositions for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.

NOVEL ALKYNE COMPOUNDS WITH AN MCH-ANTAGONISTIC ACTION AND MEDICAMENTS CONTAINING SAID COMPOUNDS

The invention relates to alkyne compounds of general formula (I), in which the groups and radicals A, B, W, X, Y, Z, R1 and R2 are defined as cited in claim 1. The invention also relates to medicaments containing at least one inventive alkyne. As a result of the antagonistic action against the MCH-receptor, the inventive medicaments are suitable for treating metabolic disorders and/or eating disorders, in particular adiposity and diabetes.