59507-48-1 Usage
General Description
1-(2-chlorobenzyl)piperidine is a chemical compound that consists of a piperidine ring with a benzyl group substituted at the 1-position and a chlorine atom substituted at the 2-position. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. 1-(2-chlorobenzyl)piperidine has been studied for its potential applications in medicinal chemistry, particularly in the development of new therapeutic agents for various medical conditions. It is also used in research to explore its properties and potential biological activities. 1-(2-CHLOROBENZYL)PIPERIDINE is known for its diverse range of chemical and pharmacological properties, making it an important building block in the field of organic synthesis and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 59507-48-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,5,0 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 59507-48:
(7*5)+(6*9)+(5*5)+(4*0)+(3*7)+(2*4)+(1*8)=151
151 % 10 = 1
So 59507-48-1 is a valid CAS Registry Number.
59507-48-1Relevant articles and documents
Photoredox-catalyzed Direct Reductive Amination of Aldehydes without an External Hydrogen/Hydride Source
Alam, Rauful,Molander, Gary A.
supporting information, p. 2680 - 2684 (2018/05/22)
The direct reductive amination of aromatic aldehydes has been realized using a photocatalyst under visible light irradiation. The single electron oxidation of an in situ formed aminal species generates the putative α-amino radical that eventually delivers the reductive amination product. This method is operationally simple, highly selective, and functional group tolerant, which allows the direct synthesis of benzylic amines by a unique mechanistic pathway.
An expedient three-component synthesis of tertiary benzylamines
Le Gall, Erwan,Decompte, Alexandre,Martens, Thierry,Troupel, Michel
experimental part, p. 249 - 254 (2010/04/05)
A Mannich-like zinc-mediated three-component reaction of aromatic halides, amines, and paraformaldehyde is described. This procedure, which involves the in situ formation of arylzinc reagents, allows the straightforward synthesis of a range of functionalized tertiary benzylamines. Georg Thieme Verlag Stuttgart.
