5955-64-6Relevant academic research and scientific papers
Synthesis of primary: N -arylthioglyoxamides from anilines, elemental sulfur and primary C-H bonds in acetophenones
Bui, Thuy T.,Le, Ha V.,Nguyen, Nguyen H. K.,Nguyen, Tung T.,Phan, Nam T. S.,To, Tuong A.,Tran, Khoa M.
, p. 44743 - 44746 (2020)
A simple method for coupling of anilines, acetophenones, and elemental sulfur to afford N-arylthioglyoxamides has been developed. Reactions proceeded in the presence of Na2SO3 and DMSO, thus eliminating the need for transition metals and external oxidants. Functionalities such as halogen, ester, methylthio, and heterocycle groups were compatible with the conditions. Electron-poor acetophenones sometimes gave isosteric glyoxamides. This journal is
Desulfurizing agent for thioamides
Polushina,Zavarzin,Krayushkin,Rodionova,Yarovenko
, p. 383 - 385 (2021/03/03)
Thioamides treated with thionyl chloride in an ionic liquid were successfully converted into amides.
New synthesis of 2-aroylbenzothiazolesviametal-free domino transformations of anilines, acetophenones, and elemental sulfur
Doan, Khang V.,Doan, Son H.,Huynh, Tien V.,Luong, Ngoc T. K.,Nguyen, Duyen T. P.,Nguyen, Tung T.,Phan, Nam T. S.
, p. 18423 - 18433 (2020/06/08)
A new synthesis of 2-aroylbenzothiazolesviaiodine-promoted domino transformations of anilines, acetophenones, and elemental sulfur was demonstrated. The highlights of this tandem synthesis are (1) easily available anilines and acetophenones as feedstock;
Acid-Catalyzed Condensation of o-Phenylenediammines and o-Aminophenols with α-Oxodithioesters: A Divergent and Regio? selective Synthesis of 2-Methylthio-3-Aryl/Heteroarylquinoxalines and 2-Acylbenzoxazoles
Anil, Seegehally M,Kiran, Kuppalli R,Rangappa, Kanchugarakoppal S,Sadashiva, Maralinganadoddi P,Shruthi, Jeegundipattana B,Sukrutha, Kodipura P,Swaroop, Toreshettahally R
, p. 4205 - 4214 (2019/11/14)
o-Phenylenediammines and o-Aminophenols were reacted with α-oxodithioesters in a highly regioselective fashion to give 2-methylthio-3-Aryl/heteroarylquinoxalines and 2-Acylbenzoxazoles in 55-94percent and 45-86percent, respectively, in the presence of p-T
Palladium-Catalyzed 3-Aryl-5-acyl-1,2,4-thiadiazole Formation from Ketones, Amidines, and Sulfur Powder
Wang, Zilong,Xie, Hao,Xiao, Fuhong,Guo, Yanjun,Huang, Huawen,Deng, Guo-Jun
supporting information, p. 1604 - 1607 (2017/04/06)
An efficient strategy for the preparation of 3,5-disubstituted 1,2,4-thiadiazoles from ketones, amidines, and sulfur powder under palladium-catalyzed conditions was developed. In this transformation, aromatic ketones act as both the carbon and acyl source
Na2S-mediated thionation: An efficient access to secondary and tertiary α-ketothioamides via Willgerodt-Kindler reaction of readily available arylglyoxals with amines
Saeidian, Hamid,Vahdati-Khajehi, Saleh,Bazghosha, Homeira,Mirjafary, Zohreh
, p. 700 - 710 (2015/10/19)
The task of this paper is to provide an efficient process for synthesis of secondary and tertiary α-ketothioamides via Willgerodt-Kindler reaction of readily available arylglyoxals with amines using Na2S as an effective catalyst. A plausible role for Na2S in the reaction of arylglyoxals with primary amines is proposed.
Direct synthesis of α-ketothioamides from aryl methyl ketones and amines via I2-promoted sp3 C-H functionalization
Li, Hong-Zheng,Xue, Wei-Jian,Wu, An-Xin
, p. 4645 - 4651 (2014/06/23)
A domino reaction that involves the formation of CS and C-N bonds in one process via sp3 C-H functionalization strategy has been developed. This reaction affords an efficient and direct method for the synthesis of α-ketothioamides from aryl met
