595547-23-2Relevant academic research and scientific papers
Chemoenzymatic preparation of non-racemic N-Boc-pyrrolidine-3,4-dicarboxylic acid 3-ethyl esters and their 4-hydroxymethyl derivatives
Rodriguez Sarmiento, Rosa Maria,Wirz, Beat,Iding, Hans
, p. 1547 - 1551 (2003)
For the synthesis of metalloproteinase inhibitors the (R,R)- and (S,S)-monoethyl esters of N-Boc-pyrrolidine-3,4-dicarboxylic acid were prepared as key intermediates from the trans-diester racemate by two consecutive, highly selective enzymatic reactions.
