595556-31-3

Usage

Uses

Used in Organic Synthesis:
(3R,4R)-1-[(tert-butoxy)carbonyl]-4-(ethoxycarbonyl)pyrrolidineis used as a building block for the synthesis of complex organic compounds. The presence of the tert-butoxycarbonyl and ethoxycarbonyl groups allows for further functionalization and modification of the molecule, enabling the creation of a wide range of organic compounds.
Used in Drug Development:
(3R,4R)-1-[(tert-butoxy)carbonyl]-4-(ethoxycarbonyl)pyrrolidineis used as a key intermediate in the development of new pharmaceuticals. Its unique structure and functional groups make it a promising candidate for the synthesis of bioactive molecules with potential therapeutic applications.
Used in Medicinal Chemistry:
(3R,4R)-1-[(tert-butoxy)carbonyl]-4-(ethoxycarbonyl)pyrrolidineis used as a chiral auxiliary in asymmetric synthesis, facilitating the production of enantiomerically pure compounds. This is particularly important in medicinal chemistry, where the stereochemistry of a molecule can significantly impact its biological activity and safety profile.
Further research and experimentation may reveal additional potential uses and properties of (3R,4R)-1-[(tert-butoxy)carbonyl]-4-(ethoxycarbonyl)pyrrolidine-, expanding its applications in various industries.

Upstream product

• 2459-05-4 (E)-4-ethoxy-4-oxobut-2-enoic acid 
• 623-91-6 diethyl Fumarate 
• 92486-65-2 diethyl trans-N-benzyl-pyrrolidine-3,4-dicarboxylate 
• 595547-23-2 (+/-)-trans-pyrrolidine-1,3,4-tricarboxylic acid 1-tert-butyl ester 3,4-diethyl ester 

Downstream Products

• 865451-71-4 (3R,4R)-4-(4-chlorophenylcarbamoyl)pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester 
• 865451-74-7 (3R,4R)-4-[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)phenylcarbamoyl]pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester 

Relevant academic research and scientific papers

TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF

A compound represented by Formula [I]: or pharmaceutically acceptable salt thereof, wherein each symbol is as defined in the description.

NEW SOLID FORMS OF FXA INHIBITORS

The invention is concerned with crystalline forms or amorphous forms of a pyrrolidine- 3,4-dicarboxamide derivative, which is useful as an active ingredient of medicaments for the diseases which can be treated by the coagulation factor Xa inhibitors.

PROCESSES FOR THE PREPARATION OF (3R, 4R) -N- (4 -CHLOROPHENYL) -1- (2, 2-DIFLUOROETHYL) -N' - [2-FLUORO-4- (2-OXO-1 (2H) -PYRIDINYL) PHENYL] -3, 4-PYRROLIDINEDICARBOXAMIDE

The invention is concerned with processes for the manufacture of pyrrolidine-3,4- dicarboxamide derivative of formula (I), and the intermediates useful for those processes.

NOVEL PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVES

The invention is concerned with novel pyrrolidine-3,4-dicarboxamide derivatives of Formula (I) ; wherein Rl to R9 and X are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These c

Chemoenzymatic preparation of non-racemic N-Boc-pyrrolidine-3,4-dicarboxylic acid 3-ethyl esters and their 4-hydroxymethyl derivatives

For the synthesis of metalloproteinase inhibitors the (R,R)- and (S,S)-monoethyl esters of N-Boc-pyrrolidine-3,4-dicarboxylic acid were prepared as key intermediates from the trans-diester racemate by two consecutive, highly selective enzymatic reactions.