5957-92-6

Usage

Uses

Used in Pharmaceutical Industry:
4-(3-Chloro-phenyl)-pyridine is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable component in the development of new drugs, contributing to the creation of innovative therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 4-(3-Chloro-phenyl)-pyridine also serves as an intermediate, playing a crucial role in the synthesis of different agrochemicals. Its application helps in developing effective solutions for agricultural challenges.
Used in Chemical Synthesis:
4-(3-Chloro-phenyl)-pyridine is employed as a building block in the production of various specialty chemicals. Its synthetic versatility allows it to be a key component in the creation of a wide range of chemical products.
Used in Medicinal Chemistry Research:
Due to its potential biological activity, 4-(3-Chloro-phenyl)-pyridine is studied for its role in the development of new drugs. Researchers explore its properties to enhance the discovery and design of novel pharmaceutical compounds with improved therapeutic effects.

Upstream product

• 110-86-1 pyridine 
• 108-42-9 3-chloro-aniline 
• 625-99-0 3-iodochlorobenzene 
• 1692-15-5 4-pyridylboronic acid 
• 108-37-2 1-bromo-3-chlorobenzene 
• 15854-87-2 4-iodopyridine 
• 108-90-7 chlorobenzene 

Downstream Products

• 39795-13-6 C₁₂H₁₁ClN⁽¹⁺⁾*I^(1-) 
• 92929-24-3 4-(3-chlorophenyl)pyridine 1-oxide 

Relevant academic research and scientific papers

Synthesis of Vinylphenylpyridine and Living Anionic Polymerization

Provided are a vinyl-biphenylpyridine monomer and a polymer thereof. More particularly, the present invention provides a vinyl-biphenylpyridine monomer having a side chain of pyridine or phenylpyridine as a functional group, a homopolymer of which molecul

Sodium 2-(2-pyridin-3-ylethylamino)ethyl sulfonate: an efficient ligand and base for palladium-catalyzed Suzuki reaction in aqueous media

PdCl2, N-donor ligand and base mediated Suzuki coupling reaction of aryl halides and arylboronic acid in water are described. The corresponding Suzuki products were obtained in good to excellent yields.

Vesicular monoamine transporter substrate/inhibitor activity of MPTP/MPP+ derivatives: A structure-activity study

The active metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), N-methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease. Inhibition of mitochondrial complex

SYNTHESIS OF VINYLPHENYLPYRIDINE AND LIVING ANIONIC POLYMERIZATION

Provided are a vinyl-biphenylpyridine monomer and a polymer thereof. More particularly, the present invention provides a vinyl-biphenylpyridine monomer having a side chain of pyridine or phenylpyridine as a functional group, a homopolymer of which molecul

Synthesis of functionalized 4-phenyl-pyridines via electrochemically prepared organozinc reagents

The efficient and convenient synthesis of various functionalized 4-phenyl-pyridines 2 is described. The key step of the procedure is the electrochemical formation of aromatic organozinc reagents 1 and their coupling with pyridinium salts. Intermediate 1,4

THE PYRIDYL CATION AS A REACTIVE INTERMEDIATE IN THE PHOTOREACTION OF IODOPYRIDINES WITH BENZENES

The electrophilic behavior of the reactive entity in the photosubstitution of benzenes with 2-iodopyridine was found to be ascribable to the intermediary 2-pyridyl cation, rather than the electrophilic 2-pyridyl radical.

Studies on Tertiary Amine Oxides. LXXVII. The Pseudo-Gomberg Reaction of 4- and 2-Aminopyridine 1-Oxides

The 1-oxido-4-pyridyl radical generated by the reaction of 4-aminopyridine 1-oxide with amyl nitrite reacted smoothly with aromatic hydrocarbons, including five-membered heterocycles, i.e. thiophene, fyran and pyrrole, to give the arylated products when acetic acid was used as the solvent.The relative rates of reaction with the 1-oxido-4-pyridyl radical indicated that this radical is electrophilic, and this finding was supported by a comparison of molecular orbital energy levels. 2-Aminopyridine 1-oxide also undergoes a similar reaction.Keywords - pyridine N-oxide; Gomberg reaction; phenylpyridine; thienylpyridine; furylpyridine; 1-methanesulfonyl-pyrrolylpyridine; 1-oxido-4-pyridyl radical; molecular orbital; highperformance liquid chromatography