596122-61-1

Upstream product

• 919087-35-7 (E)-1-chloro-8-phenyl-1-octene-3,5,7-triyne 
• 75-77-4 chloro-trimethyl-silane 
• 4526-07-2 1,4-bis(trimethylsilyl)-1,3-butadiyne 
• 596122-59-7 7-phenyl-1-trimethylsilyl-1,3,6-heptatriyne-5-one 
• 536-74-3 phenylacetylene 
• 18685-03-5 (E)-1-(4-chlorobut-3-en-1-ynyl)benzene 
• 919087-27-7 (E)-1-chloro-6-phenyl-1-hexene-3,5-diyne 
• 596122-60-0 7-phenyl-1-trimethylsilyl-(5-dibromomethylidene)-1,3,6,-heptatriyne 

Downstream Products

• 1258456-73-3 C₁₉H₁₁F₃O₃ 

Relevant academic research and scientific papers

Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling

(Diagram presented) Iteration of a Pd-catalyzed reaction of alkynyl- and oligoynylzincs with (E)-ICH=CHCl followed by metalation-termination with electrophiles(E) has provided a linear route to conjugated tri- and tetraynes, and Pd-catalyzed monoalkynylation of 1,1-dibromoenynes accompanied by dehydrobromination has provided a convergent route to conjugated tri-, tetra-, and pentaynes. Both display unprecedented high efficiency and selectivity.

Alkyne migration in alkylidene carbenoid species: A new method of polyyne synthesis

The synthesis of conjugated polyyne structures via a modification of the Fritsch-Buttenberg-Wiechell (FBW) rearrangement is reported. Our adaptation provides for the 1,2-migration of an alkyne in a carbene/carbenoid intermediate that is conveniently effec