59666-15-8

Basic information

• Product Name: 7-chloro-2-methylquinoline-4-carboxylic acid
• CAS NO: 59666-15-8
• Molecular Formula: C₁₁H₈ClNO₂
• Molecular Weight: 221.6397
• Mol File: 59666-15-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 377.3°C at 760 mmHg
• Flash Point: 182°C
• Density: 1.406g/cm³
• Vapor Pressure: 2.3E-06mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: 7-chloro-2-methylquinoline-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-2-methylquinoline-4-carboxylic acid(59666-15-8)
• EPA Substance Registry System: 7-chloro-2-methylquinoline-4-carboxylic acid(59666-15-8)

Safety Data

• Hazardous Substances Data: 59666-15-8(Hazardous Substances Data)

Upstream product

• 67-64-1 acetone 

Downstream Products

• 81735-39-9 7-Chloro-2-(hydroxyimino-methyl)-quinoline-4-carboxylic acid 
• 81735-36-6 7-Chloro-2-[(2-sulfooxy-ethyl)-hydrazonomethyl]-quinoline-4-carboxylic acid 
• 81735-33-3 C₁₂H₉ClN₄O₂S 
• 81735-35-5 7-Chloro-2-(methyl-hydrazonomethyl)-quinoline-4-carboxylic acid 

Relevant articles and documents

Utilizing Solubility differences to achieve regiocontrol in the synthesis of substituted quinoline-4-carboxylic acids

A practical method for the regiocontrolled synthesis of substituted quinoline-4-carboxylic acids is described. Solubility differences between the product quinoline regioisomers enable their facile separation, thus avoiding any challenging chromatographic purifications and allowing access to highly substituted quinoline compounds in three steps from commercially available anilines.