59675-63-7

Usage

Uses

Used in Organometallic Chemistry:
(E)-(2-(pyridin-2-yl)vinyl)diphenylphosphine oxide is used as a ligand for organometallic chemistry applications due to its ability to form stable complexes with metal ions. This enhances the reactivity and selectivity of the resulting organometallic compounds.
Used in Catalysis:
In the field of catalysis, (E)-(2-(pyridin-2-yl)vinyl)diphenylphosphine oxide is used as a ligand to create metal complexes that can act as catalysts in various chemical reactions. Its unique structure allows for the fine-tuning of catalytic properties, making it a valuable tool in the development of new and improved catalysts.
Used in the Synthesis of Complex Organic Molecules:
(E)-(2-(pyridin-2-yl)vinyl)diphenylphosphine oxide is used as a building block for the synthesis of more complex organic molecules. Its versatile structure allows for the creation of a wide range of compounds with diverse properties and potential applications.
Used in the Design of Metal Complexes for Catalytic Processes:
The phosphorous component of (E)-(2-(pyridin-2-yl)vinyl)diphenylphosphine oxide makes it useful in the design and synthesis of metal complexes for various catalytic processes. These complexes can be employed in a variety of chemical reactions, contributing to the advancement of chemical synthesis and process efficiency.
Used in Pharmaceutical Industry:
(E)-(2-(pyridin-2-yl)vinyl)diphenylphosphine oxide may also find applications in the pharmaceutical industry, where its unique structure and properties can be utilized in the development of new drugs or drug delivery systems.
Used in Material Science:
In material science, (E)-(2-(pyridin-2-yl)vinyl)diphenylphosphine oxide could be used to develop new materials with specific properties, such as improved conductivity or enhanced stability, by incorporating its structure into the design of these materials.

Upstream product

• 1945-84-2 2-ethynylpyridine 
• 4559-70-0 Diphenylphosphine oxide 
• 54495-51-1 (E)-3-(2-pyridyl)acrylic acid 
• 1121-60-4 pyridine-2-carbaldehyde 
• 1831-63-6 diphenylphosphorylacetic acid 

Downstream Products

• 94394-57-7 (E)-diphenyl(2-(pyridin-2-yl)vinyl)phosphine sulfide 

Relevant academic research and scientific papers

Knoevenagel Condensation of Phosphinoylacetic Acids with Aldehydes: An Efficient One-Pot Strategy for the Synthesis of P-Functionalized Alkenyl Compounds

A wide range of commercially available aldehydes have been applied to Knoevenagel condensation reaction to give E -alkenylphosphine oxides and vinylphosphine oxides. The readily available phosphinoylacetic acids derived from P(O)-H compounds were used as the starting materials in the reaction, providing a highly stereoselective and efficient method for constructing α,β-unsaturated phosphine oxides. Moreover, this simple and practical procedure provides an alternative and more environmentally friendly synthesis strategy for this type of P-functionalized alkenyl compounds.

Transition-metal-free C-P bond formation via decarboxylative phosphorylation of cinnamic acids with P(O)H compounds

A novel, transition-metal-free phosphorylation of cinnamic acids with P(O)H compounds has been developed via radical-promoted decarboxylation under mild conditions. This method provides simple, efficient, and versatile access to valuable (E)-alkenylphosphine oxides in satisfactory yields with a wide variety of substrates.

Nickel(II)-magnesium-catalyzed cross-coupling of 1,1-dibromo-1-alkenes with diphenylphosphine oxide: One-pot synthesis of (E)-1-alkenylphosphine oxides or bisphosphine oxides

A novel nickel(II)-magnesium-mediated cross-coupling of diphenylphosphine oxide with a variety of 1,1-dibromo-1-alkenes has been developed, which provides a powerful and general methodology for the stereoselective synthesis of various (E)-1-alkenylphosphine oxides or bisphosphine oxides, with operational simplicity of the procedure, good to high yields and broad substrate applicability. Mechanistic studies reveal that the reaction might involve a Hirao reduction, cross-coupling and Michael addition. Copyright

Diphosphino-functionalized MCM-41-immobilized rhodium complex: A highly efficient and recyclable catalyst for the hydrophosphinylation of terminal alkynes

Diphosphino-functionalized MCM-41-immobilized rhodium complex (MCM-41-2P-RhCl3) was conveniently synthesized from commercially available and cheap γ-aminopropyltriethoxysilane via immobilization on mesoporous MCM-41, followed by reacting with diphenylphosphinomethanol and rhodium chloride. It was found that this heterogeneous rhodium complex is a highly efficient catalyst for the hydrophosphinylation of terminal alkynes with diphenylphosphine oxide and can be recovered and recycled by a simple filtration of the reaction solution and used for at least 10 consecutive trials without any decreases in activity.