596815-04-2

Basic information

• Product Name: 4H-Pyrido[1,2-a]pyrimidine-3-carboxaldehyde, 4-oxo-2-(1-pyrrolidinyl)-, 3-(phenylhydrazone)
• CAS NO: 596815-04-2
• Molecular Formula: C19H19N5O
• Molecular Weight: 333.393
• Mol File: 596815-04-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4H-Pyrido[1,2-a]pyrimidine-3-carboxaldehyde, 4-oxo-2-(1-pyrrolidinyl)-, 3-(phenylhydrazone)(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyrido[1,2-a]pyrimidine-3-carboxaldehyde, 4-oxo-2-(1-pyrrolidinyl)-, 3-(phenylhydrazone)(596815-04-2)
• EPA Substance Registry System: 4H-Pyrido[1,2-a]pyrimidine-3-carboxaldehyde, 4-oxo-2-(1-pyrrolidinyl)-, 3-(phenylhydrazone)(596815-04-2)

Safety Data

• Hazardous Substances Data: 596815-04-2(Hazardous Substances Data)

Upstream product

• 111680-73-0 2-(1-pyrrolidinyl)-4-oxo-4H-pyrido<1,2-a>pyrimidine-3-carbaldehyde 
• 100-63-0 phenylhydrazine 
• 17481-62-8 2-chloro-4-oxo-4H-pyrido<1,2-a>pyrimidine 3-carboxaldehyde 

Downstream Products

• 84292-30-8 2-(1-pirrolidinil)-4H-pirido<1,2-a>pirimidin-4-one 
• 23245-11-6 dimethyl 1-phenylpyrazole-4,5-dicarboxylate 
• 885-94-9 ethyl 1-phenylpyrazole-4-carboxylate 
• 720-71-8 ethyl 1-phenyl-2-pyrazoline-4-carboxylate 
• 111680-73-0 2-(1-pyrrolidinyl)-4-oxo-4H-pyrido<1,2-a>pyrimidine-3-carbaldehyde 

Relevant articles and documents

Generation of NH-azomethine imine intermediates through the 1,2-hydrogen shift of hydrazones and their intermolecular cycloaddition reaction with olefinic dipolarophiles

The thermal 1,2-hydrogen shift of the hydrazone generates the NH-azomethine imine intermediate in the 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde system under mild conditions. Therein, the resulting NH-azomethine imine should be stabilized by forming an internal hydrogen bond with the carbonyl oxygen at the 4-position. Its smooth stereoselective intermolecular cycloaddition reaction with olefinic dipolarophiles giving pyrazolidine derivatives is discussed.