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Usage

Uses

Used in Pharmaceutical Research:
Ethyl 1-phenyl-1H-pyrazole-4-carboxylate, 97% is used as a key intermediate for the synthesis of various drugs and biologically active compounds. Its unique structure and reactivity make it a valuable component in the development of new pharmaceutical agents.
Used in Organic Synthesis:
In the field of organic synthesis, Ethyl 1-phenyl-1H-pyrazole-4-carboxylate, 97% is utilized as a building block for the creation of new chemical compounds. Its high purity ensures reliable and efficient reactivity in chemical reactions, contributing to the advancement of synthetic chemistry.
Used in Medicinal Chemistry:
Ethyl 1-phenyl-1H-pyrazole-4-carboxylate, 97% is employed as a structural component in the design and synthesis of novel therapeutic agents. Its presence in the molecular framework can influence the pharmacological properties of the resulting compounds, making it an important tool in medicinal chemistry.
Used in Agricultural Chemistry:
In agricultural applications, Ethyl 1-phenyl-1H-pyrazole-4-carboxylate, 97% is used as a precursor in the development of new agrochemicals, such as pesticides and herbicides. Its versatility in chemical reactions allows for the creation of compounds with targeted biological activity against pests and weeds.
Overall, the high purity and unique chemical properties of Ethyl 1-phenyl-1H-pyrazole-4-carboxylate, 97% make it a valuable asset in various scientific and industrial fields, driving innovation and the development of new products.

Upstream product

• 100-63-0 phenylhydrazine 
• 98-80-6 phenylboronic acid 
• 37622-90-5 4-ethoxycarbonylpyrazole 
• 71-43-2 benzene 
• 508191-77-3 3-phenylsydnone 
• 623-47-2 propynoic acid ethyl ester 
• 26788-89-6 phenylazo 4-methylphenyl sulfone 
• 6415-68-5 N-nitroso-N-phenylglycine 
• 103-01-5 N-Phenylglycine 
• 16520-62-0 4-Phenyl-1-butyne 
• 34780-29-5 3-oxo-propionic acid ethyl ester 
• 92385-43-8 3-(N,N-dimethylamino)-2-ethoxycarbonylacrolein 
• 292638-85-8 acrylic acid methyl ester 
• 596815-04-2 4-oxo-2-(pyrrolidin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde phenylhydrazone 

Downstream Products

• 70817-26-4 (1-phenyl-1H-pyrazol-4-yl)methanol 
• 1134-50-5 4-carboxy-1-phenylpyrazole 
• 91062-67-8 1-Phenyl-4-(2-bromoacetyl)pyrazole 
• 267641-97-4 1-Phenyl-1H-pyrazole-4-carbonyl chloride 
• 1621514-54-2 ethyl 1-(2-allylphenyl)-1H-pyrazole-4-carboxylate 
• 137813-14-0 Methyl 4-<4-(1-phenylpyrazolyl)>-2-thiazolylacetate hydrobromide 
• 137577-01-6 4-<4-(1-Phenylpyrazolyl)>-2-thiazolylacetic acid 
• 153863-63-9 4-Bromomethyl-1-phenyl-1H-pyrazole 
• 35715-77-6 (1-phenyl-1H-pyrazol-4-yl)-acetic acid 
• 51412-23-8 (1-phenyl-1H-pyrazol-4-yl)-acetonitrile 

Relevant academic research and scientific papers

Addition Reaction of Immonium Benzotriazolates To Acetylenic Esters

1-Dialkylaminomethylbenzotriazoles react with ethyl propiolate and dimethyl acetylenedicarboxylate by addition of the benzotriazole anion followed by the immonium cation.The benzotriazolyl group in the products undergoes facile nucleophilic displacement.

Unveiling Potent Photooxidation Behavior of Catalytic Photoreductants

We describe a photocatalytic system that reveals latent photooxidant behavior from one of the most reducing conventional photoredox catalysts, N-phenylphenothiazine (PTH). This aerobic photochemical reaction engages difficult to oxidize feedstocks, such as benzene, in C(sp2)-N coupling reactions through direct oxidation. Mechanistic studies are consistent with activation of PTH via photooxidation and with Lewis acid cocatalysts scavenging inhibitors inextricably formed in this process.

Synthesis of pyrazole-carboxamides and pyrazole-carboxylic acids derivatives: Simple methods to access powerful building blocks

Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.

NOVEL COMPOUND AS MTOR INHIBITOR AND USE THEREOF

The present invention relates to a novel compound as an mTOR inhibitor and a use thereof and, more specifically, to a novel compound represented by formula 1 that exhibits mTOR inhibitory activity and a pharmaceutical composition comprising same as an act

Electrophotocatalysis with a Trisaminocyclopropenium Radical Dication

Visible-light photocatalysis and electrocatalysis are two powerful strategies for the promotion of chemical reactions. Here, these two modalities are combined in an electrophotocatalytic oxidation platform. This chemistry employs a trisaminocyclopropenium (TAC) ion catalyst, which is electrochemically oxidized to form a cyclopropenium radical dication intermediate. The radical dication undergoes photoexcitation with visible light to produce an excited-state species with oxidizing power (3.33 V vs. SCE) sufficient to oxidize benzene and halogenated benzenes via single-electron transfer (SET), resulting in C?H/N?H coupling with azoles. A rationale for the strongly oxidizing behavior of the photoexcited species is provided, while the stability of the catalyst is rationalized by a particular conformation of the cis-2,6-dimethylpiperidine moieties.

L -(-) -Quebrachitol as a Ligand for Selective Copper(0)-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles

l-(-)-Quebrachitol (QCT) has been found as a ligand of copper powder for selective N-arylation of nitrogen-containing heterocycles with aryl halides. Furthermore, another potential catalytic system (copper powder/QCT/t-BuOK) was successfully adapted to unactivated aryl chlorides.

Copper-catalyzed C–N cross-coupling of arylboronic acids with N-acylpyrazoles

A copper-catalyzed C–N bond forming reaction of arylboronic acids and N-acylpyrazoles was developed. This procedure used N-acetyl protected pyrazoles as starting material instead of free pyrazoles (NH). The reaction worked under neutral conditions and did not require any base or ligand. The reaction showed good functional group tolerance.

Cu-promoted sydnone cycloadditions of alkynes: Scope and mechanism studies

Cu salts have been found to promote the cycloaddition reaction of sydnones and terminal alkynes, providing significant reduction in reaction times. Specifically, the use of Cu(OTf)2 is found to provide 1,3-disubstituted pyrazoles, whereas simpl

nBu3P-catalyzed desulfonylative [3 + 2] cycloadditions of allylic carbonates with arylazosulfones to pyrazole derivatives

Highly efficient nBu3P-catalyzed desulfonylative [3 + 2] cycloadditions of allylic carbonates with arylazosulfones were developed for the synthesis of pyrazole derivatives. The reactions proceed smoothly under mild conditions to gene

One-pot synthesis of 1,4-disubstituted pyrazoles from arylglycines via copper-catalyzed sydnone-alkyne cycloaddition reaction

A robust method for constructing 1,4-pyrazoles from arylglycines was developed using the copper-catalyzed sydnone-alkyne cycloaddition reaction. The procedure offers a straightforward and general route to the pyrazole heterocycle through a three-step one-pot procedure.