59724-72-0 Usage
Uses
Used in Pharmaceutical Industry:
3-(4-methoxy-benzenesulfonylamino)-propionic acid is used as a novel therapeutic agent for the treatment of Alzheimer's disease. Its chemical structure allows it to potentially interact with specific targets in the brain, offering a new approach to managing the cognitive decline associated with this neurodegenerative condition.
Additionally, 3-(4-methoxy-benzenesulfonylamino)-propionic acid is used as a targeting agent for the hepatitis C virus helicase. By inhibiting the helicase enzyme, 3-(4-methoxy-benzenesulfonylamino)-propionic acid can disrupt the replication cycle of the virus, providing a potential treatment strategy for hepatitis C infection.
Check Digit Verification of cas no
The CAS Registry Mumber 59724-72-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,7,2 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 59724-72:
(7*5)+(6*9)+(5*7)+(4*2)+(3*4)+(2*7)+(1*2)=160
160 % 10 = 0
So 59724-72-0 is a valid CAS Registry Number.
59724-72-0Relevant academic research and scientific papers
In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase
Bassetto, Marcella,Leyssen, Pieter,Neyts, Johan,Yerukhimovich, Mark M.,Frick, David N.,Courtney-Smith, Matthew,Brancale, Andrea
supporting information, p. 1115 - 1131 (2016/11/09)
A structure-based virtual screening of commercial compounds was carried out on the HCV NS3 helicase structure, with the aim to identify novel inhibitors of HCV replication. Among a selection of 13 commercial structures, one compound was found to inhibit the subgenomic HCV replicon in the low micromolar range. Different series of new piperazine-based analogues were designed and synthesised, and among them, several novel structures exhibited antiviral activity in the HCV replicon assay. Some of the new compounds were also found to inhibit HCV NS3 helicase function in?vitro, and one directly bound NS3 with a dissociation constant of 570?±?270?nM.
