59726-39-5

Basic information

• Product Name: Propanedioic acid, (1-Methylethyl)-2-propenyl-, diethyl ester
• Synonyms: Propanedioic acid, (1-Methylethyl)-2-propenyl-, diethyl ester
• CAS NO: 59726-39-5
• Molecular Weight: 242.315
• Mol File: 59726-39-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, (1-Methylethyl)-2-propenyl-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, (1-Methylethyl)-2-propenyl-, diethyl ester(59726-39-5)
• EPA Substance Registry System: Propanedioic acid, (1-Methylethyl)-2-propenyl-, diethyl ester(59726-39-5)

Safety Data

• Hazardous Substances Data: 59726-39-5(Hazardous Substances Data)

Usage

Uses

(1-Methylethyl)-2-propenyl Diethyl Ester Propanedioic Acid is an intermediate in the synthesis of Propanedioic acid, 2-(1-methylethyl)-2-propyl-, 1,3-diethyl ester (M305005), which is used in the cyclization of appropriate reactants.Intermediate in barbiturate products.

Upstream product

• 2049-80-1 (2-propenyl)propanedioic acid diethyl ester 
• 75-26-3 isopropyl bromide 
• 759-36-4 diethyl isopropylmalonate 
• 106-95-6 allyl bromide 
• 75-30-9 2-iodo-propane 
• 64-17-5 ethanol 
• 609-08-5 Diethyl methylmalonate 
• 105-53-3 diethyl malonate 

Downstream Products

• 1861-21-8 narconumal 
• 4375-26-2 allyl-isopropyl-malonic acid 
• 105985-99-7 2-Isopropyl-pent-4-enoic acid 3-phenoxy-benzyl ester 
• 1575-71-9 2-isopropylpent-4-enoic acid 
• 74607-22-0 5-allyl-5-isopropyl-2-thio-barbituric acid 
• 77-02-1 aprobarbital 

Relevant articles and documents

METHOD FOR PREPARING APRONAL AND INTERMEDIATE THEREOF

PROBLEM TO BE SOLVED: To provide a simple, cost-effective and improved method for synthesizing apronal and an intermediate alkyl 2-isopropyl-4-pentenoate used in the synthesis of allylisopropylacetylurea of apronal. SOLUTION: There is provided a method including a step of reacting an alkyl 2-isopropyl-4-pentenoate with an alkali metal salt such as sodium urea in the presence of an aprotic polar solvent or a mixture of solvents to obtain apronal of the following formula (1). In addition, the present invention also includes a method for preparing the intermediate alkyl 2-isopropyl-4-pentenoate by dealkoxycarbonylation of dialkylallyl isopropyl malonate. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

Intramolecular formal [4+2] cycloaddition of 3-ethoxycyclobutanones and alkenes

Intramolecular formal [4+2] cycloaddition between 3-ethoxycyclobutanones and a carbon-carbon double bond to the corresponding bicyclo[4.n.0]alkan-2-one derivatives proceeded effectively by using ethylaluminium dichloride. The Royal Society of Chemistry 20

Substituted oxotremorine derivatives and pharmaceutical use thereof

This disclosure describes novel substituted oxotremorine derivatives of formula I having nitrogen, oxygen or sulfur groups and the prodrug forms of these derivatives. The compounds have cholinergic activity. Also disclosed are methods for treating disease