59741-04-7

Usage

Uses

Used in Pharmaceutical Industry:
2-METHOXY-5-METHYLPHENYL ISOCYANATE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to form a wide range of biologically active molecules. Its reactivity allows for the creation of diverse drug candidates that can target various medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2-METHOXY-5-METHYLPHENYL ISOCYANATE is utilized as a building block in the development of pesticides and other crop protection agents. Its incorporation into these products contributes to enhanced efficacy and selectivity in agricultural applications.
Used in Polyurethane Production:
2-METHOXY-5-METHYLPHENYL ISOCYANATE is used as a reagent in the production of polyurethane foams and elastomers, contributing to the formation of materials with specific properties such as flexibility, durability, and insulation capabilities, which are valuable in various industrial and consumer products.
Used in Research and Development:
As a highly reactive chemical, 2-METHOXY-5-METHYLPHENYL ISOCYANATE is also employed in research and development settings to explore new chemical reactions and syntheses, potentially leading to the discovery of new compounds and materials with unique applications.

InChI:InChI=1/C9H9NO2/c1-7-3-4-9(12-2)8(5-7)10-6-11/h3-5H,1-2H3

Upstream product

• 75-44-5 phosgene 
• 120-71-8 Cresidine 

Downstream Products

• 38103-27-4 1-{[(E)-4-Chloro-2-methyl-phenylimino]-methyl}-3-(2-methoxy-5-methyl-phenyl)-1-methyl-urea 
• 114559-64-7 1-(2-Methoxy-5-methyl-phenyl)-3-((1R,3R,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-urea 
• 363140-31-2 N-(9-benzyl-9-azabicyclo[3.3.1]nonan-3α-yl)-N'-(2-methoxy-5-methylphenyl)carbamate 
• 363140-16-3 N-(8-benzyl-8-azabicyclo[3.2.1]octan-3α-yl)-N'-(2-methoxy-5-methylphenyl)carbamate 
• 457099-15-9 1-(5-Methyl-pyrazin-2-yl)-3-[5-methyl-2-(pyridin-2-yloxy)-phenyl]-urea 
• 913181-55-2 3-{4-[3-(2-methoxy-5-methylphenyl)ureido]phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamide 
• 1202810-87-4 C₂₇H₂₅N₇O₂ 
• 1270915-86-0 3-(3-(2-methoxy-5-methylphenyl)ureido)-2-methylpropanoic acid 
• 717899-12-2 1-[3-(4-amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-3-(2-methoxy-5-methyl-phenyl)-urea 
• 717897-51-3 1-[3-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-3-(2-methoxy-5-methyl-phenyl)-urea 
• 1080828-61-0 1-[3-(4-amino-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-3-(2-methoxy-5-methyl-phenyl)-urea 

Relevant academic research and scientific papers

5-Hydroxytryptamine (5-HT3) Receptor Antagonists. 3. Ortho-Substituted Phenylureas

A novel series of potent 5-HT3 receptor antagonists, ortho-substituted phenylureas 6a-z, is described in which the 5-membered ring of the previously reported indazoles and indolines has been replaced by an intramolecular hydrogen bond.High potency was found both for carbamate 6a and urea 6b.Granatane 6c was less potent than the equivalent tropane.Phenylurea 11c lacking the ortho substituent was inactive.Whereas further substitution could not be tolerated in the aromatic ring, activity was retained with a range of O-alkyl groups, compounds 6k-t.In addition, good activity was found for ortho ester 6u and sulfonamide 6x.The ortho-substituted phenylureas can therefore be regarded as bioisosteres of the 6,5-heterocycles indole, indazole, and indoline.