59741-04-7 Usage
General Description
2-METHOXY-5-METHYLPHENYL ISOCYANATE is a chemical compound with the molecular formula C9H9NO2. It is an isocyanate, which means it contains the functional group -NCO. 2-METHOXY-5-METHYLPHENYL ISOCYANATE is used in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It is also used as a reagent in the production of polyurethane foams and elastomers. 2-METHOXY-5-METHYLPHENYL ISOCYANATE is a highly reactive and potentially hazardous chemical and should be handled with caution in a controlled laboratory setting following proper safety protocols.
Check Digit Verification of cas no
The CAS Registry Mumber 59741-04-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,7,4 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 59741-04:
(7*5)+(6*9)+(5*7)+(4*4)+(3*1)+(2*0)+(1*4)=147
147 % 10 = 7
So 59741-04-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NO2/c1-7-3-4-9(12-2)8(5-7)10-6-11/h3-5H,1-2H3
59741-04-7Relevant articles and documents
5-Hydroxytryptamine (5-HT3) Receptor Antagonists. 3. Ortho-Substituted Phenylureas
Bermudez, Jose,Dabbs, Steven,King, Frank D.
, p. 1932 - 1935 (2007/10/02)
A novel series of potent 5-HT3 receptor antagonists, ortho-substituted phenylureas 6a-z, is described in which the 5-membered ring of the previously reported indazoles and indolines has been replaced by an intramolecular hydrogen bond.High potency was found both for carbamate 6a and urea 6b.Granatane 6c was less potent than the equivalent tropane.Phenylurea 11c lacking the ortho substituent was inactive.Whereas further substitution could not be tolerated in the aromatic ring, activity was retained with a range of O-alkyl groups, compounds 6k-t.In addition, good activity was found for ortho ester 6u and sulfonamide 6x.The ortho-substituted phenylureas can therefore be regarded as bioisosteres of the 6,5-heterocycles indole, indazole, and indoline.
