59749-78-9

Basic information

• Product Name: 1H-Indene, 3-(4-chlorophenyl)-
• CAS NO: 59749-78-9
• Molecular Formula: C15H11Cl
• Molecular Weight: 226.705
• Mol File: 59749-78-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-Indene, 3-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indene, 3-(4-chlorophenyl)-(59749-78-9)
• EPA Substance Registry System: 1H-Indene, 3-(4-chlorophenyl)-(59749-78-9)

Safety Data

• Hazardous Substances Data: 59749-78-9(Hazardous Substances Data)

Upstream product

• 942512-16-5 1-bromo-2-[1-(4-chlorophenyl)ethenyl]benzene 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 591-50-4 iodobenzene 
• 58824-54-7 p-chlorophenylvinylcarbinol 
• 2142-69-0 2-bromophenyl methyl ketone 
• 104-88-1 4-chlorobenzaldehyde 
• 1075-77-0 4-chlorocinnamaldehyde 
• 71-43-2 benzene 
• 83-33-0 inden-1-one 
• 59749-76-7 1-(4-chlorophenyl)-1-indanol 
• 17151-48-3 tributyl(4-chlorophenyl)stannane 
• 150970-45-9 1H-inden-3-yl trifluoromethanesulfonate 
• 5739-37-7 4'-chloro-3-phenylpropiophenone 
• 873-77-8 (4-chlorphenyl)magnesium bromide 

Downstream Products

• 77948-77-7 2-chloro-5H-dibenzocyclohepten-11-yl 2-(4-chlorobenzyl)phenylacetate 
• 10324-04-6 2-(4-chlorobenzyl)phenylacetic acid 
• 15101-07-2 {2-[1-(4-Chloro-phenyl)-1H-inden-1-yl]-ethyl}-dimethyl-amine 

Relevant articles and documents

[Pd]-Catalyzed Intermolecular Coupling and Acid Mediated Intramolecular Cyclodehydration: One-Pot Synthesis of Indenes

An efficient one-pot synthesis of indenes from simple starting materials is presented. This process involves a dual C–C bond formation through an intermolecular Heck coupling reaction followed by acid-mediated intramolecular cyclodehydration. The strategy

Rhodium(II)- or Copper(I)-Catalyzed Formal Intramolecular Carbene Insertion into Vinylic C(sp2)?H Bonds: Access to Substituted 1H-Indenes

A rhodium(II)- or copper(I)-catalyzed formal intramolecular carbene insertion into vinylic C(sp2)?H bonds is reported herein. This method provides straightforward access to 1H-indenes with high efficiency and excellent functional-group compatibility. Mechanistically, the reaction is proposed to involve the following sequence: metal carbene formation, intramolecular nucleophilic addition of the double bond to the electron-deficient carbene carbon atom, dearomatization, and finally a 1,5-H shift.

Synthesis of indenes via aluminum chloride-promoted tandem Friedel-Crafts alkylation of arenes and cinnamaldehydes

A series of substituted indenes were synthesized from arenes and cinnamaldehydes via aluminum chloride-promoted tandem Friedel-Crafts alkylation. The scope and limitation of the tandem reaction were explored. A plausible reaction mechanism is also discuss