597564-19-7

Upstream product

• 388071-27-0 tert-butyl (1S)-2-(3,5-difluorophenyl)-1-[(2S)-oxiranyl]ethylcarbamate 
• 2740-83-2 3-(TRIFLUOROMETHYL)BENZYLAMINE 

Downstream Products

• 674311-03-6 tert-butyl (1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-{(tert-butyloxy)carbonyl-3-{(trifluoromethyl)benzyl}amino}propylcarbamate 
• 674311-09-2 tert-butyl (1S,2R)-1-(3,5-difluorobenzyl)-3-{[3-[(dipropylamino)carbonyl]-5-(1,3-oxazol-2-yl)benzoyl]-3-[(trifluoromethyl)benzyl]amino}-2-hydroxypropylcarbamate 
• 388075-42-1 (2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-{[3-(trifluoromethyl)-benzyl]amino}butan-2-ol 

Relevant academic research and scientific papers

DERIVATIVES OF PYRAZOLE 3,5-CARBOXYLATES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS

The invention relates to derivatives of pyrazole 3,5-carboxylates, of general formula (I): in which R1, R2, R3, R4, R5, X, Y, V, W and n are as defined herein. The invention also relates to salts of t

1,3-DIAMINO-2-HYDROXYPROPANE PRODRUG DERIVATIVES

The present invention relates to compounds of formula (AA), (I) and (X), useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's dis

HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention relates to novel hydroxyethylamine compounds of formula (I): (I) having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated-amyloid levels or-amyloid deposits, particularly Alzheimer's disease.