59803-33-7

Upstream product

• 1846-74-8 3-benzoyl-chromen-2-one 
• 614-16-4 Benzoylacetonitrile 
• 97-51-8 5-Nitrosalicylaldehyde 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1608160-95-7 9-(methoxycarbonyl)-2-nitro-7-phenyl-6H-benzo[c]chromen-6-one 
• 1354375-51-1 1-(4-chlorophenyl)-8-nitro-3-phenyl-4H-furo[3,4-c]chromen-4-one 
• 1354375-38-4 8-nitro-1,3-diphenyl-4H-furo[3,4-c]chromen-4-one 

Relevant academic research and scientific papers

Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions

A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylpho

Biocatalytic domino reaction: Synthesis of 2H-1-benzopyran-2-one derivatives using alkaline protease from Bacillus licheniformis

A novel BLAP (alkaline protease from Bacillus licheniformis) catalyzed synthesis of 2H-1-benzopyran-2-one derivatives was achieved by domino Knoevenagel/intramolecular transesterification reaction. The control of enzymatic chemoselectivity between Knoevenagel/intramolecular transesterification and Knoevenagel/intramolecular hemiketalization could be realized by adjusting parameters including solvent, water content and temperature. The products were obtained in acceptable yields. This BLAP catalyzed selective domino reaction provided an alternative synthetic method for 2H-1-benzopyran-2-one derivatives.