59804-36-3Relevant articles and documents
Novel chemical transformations of tenoxicam
Koczian, Kristof,Koekoesi, Jozsef,Mazak, Karoly,Noszal, Bela
, p. 2355 - 2363 (2007/10/03)
Both N- and O-substituted derivatives of the anti-inflammatory drug tenoxicam (= 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine- 3-carboxamide 1,1-dioxide; 1) were synthesized, and various chemical transformations were investigated. Bot
Thienothiazines
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, (2008/06/13)
The present invention relates to compounds of the formula STR1 wherein A together with the two carbon atoms to which it is attached forms the group STR2 AND THE BROKEN LINE REPRESENTS THE DOUBLE BOND IN GROUP (A); R1 represents a lower alkyl group; R2 represents the residue of an aromatic heterocyclic ring containing from 1 to 4 hetero atoms, which may be substituted by one or two lower alkyl groups, or a phenyl group which may be substituted by halogen, hydroxy, lower alkyl, trifluoromethyl or lower alkoxy and R3 and R4 each represent a hydrogen atom or a lower alkyl group. Also provided are methods for their preparation. The thienothiazine derivatives provided by this invention have anti-flammatory, analgesic and antirheumatic activity.