59826-46-9

Upstream product

• 83-38-5 2,6-dichlorobenzaldehyde 
• 98-86-2 acetophenone 

Downstream Products

• 129226-62-6 3-(2,6-Dichloro-phenyl)-4-(5-methyl-4-nitro-2-phenyl-2H-pyrazol-3-yl)-1-phenyl-butan-1-one 
• 133961-87-2 3-[1-(2,6-Dichloro-phenyl)-3-oxo-3-phenyl-propylsulfanyl]-propionic acid 
• 1334629-37-6 5-(2,6-dichlorophenyl)-7-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-2-sulfonamide 
• 1610434-81-5 3-(2,6-dichlorophenyl)-1-phenyl-3-(pyrrolidin-1-yl)propan-1-one 
• 1268494-19-4 C₂₂H₁₆Cl₂O₂S 
• 133961-80-5 [1-(2,6-Dichloro-phenyl)-3-oxo-3-phenyl-propylsulfanyl]-acetic acid 

Relevant academic research and scientific papers

Highly Chemoselective Solvent-Free Synthesis of 1,3,5-Triaryl-1,5-diketones: Crystallographic Investigation and Intramolecular Weak Bifurcated H Bonds Involving Aliphatic C-H Group

Several 1,3,5-triaryl-1,5-diketones have been chemoselectively synthesized under solvent-free conditions. It was found that intramolecular weak bifurcated H-bonds interaction of aliphatic C-H group plays a decisive role in the structural arrangement of 3-

Synthesis and anti-inflammatory activity of new (5 (Substituted Phenyl)-2,3-Dihydro-3-Phenylpyrazol-1-Yl) (Pyridin-3-Yl)methanone derivatives

A series of 5 (substituted phenyl)-2,3-dihydro-3-phenylpyrazol-1-yl) (pyridin-3-yl)methanone derivatives (2a-h) has been synthesized starting from acetophenone. All the synthesized compounds were evaluated for anti-inflammatory activity using carrageenan-induced inflammation in rat paw edema model. Substituted chalcone derivatives (1a-h) on treatment with isoniazid in the presence of glacial acetic acid afforded corresponding pyrazoline derivatives (2a-h). The structure of the final analogs has been confirmed on the basis of elemental analysis, Fourier transform infrared (FTIR), nuclear magnetic resonance (1H NMR), and mass spectra. Among all synthesized compounds, compounds 2c and 2b were found to be most potent in comparison with standard diclofenac. In addition, the compounds 2c and 2b were found to be less ulcerogenic.

Synthesis, molecular docking study, and cytotoxic activity of 1,3,5-triaryl pyrazole derivatives

Synthesis, molecular docking study, and cytotoxic activity of a new group of 1,3,5-triaryl pyrazole derivatives were be studied. The antiproliferative activity of the final compounds were examined in MCF-7, AGS, HT-29 and NIH3T3 cell lines by MTT assay, u

Discovery and structure activity relationships of 2-pyrazolines derived from chalcones from a pest management perspective

Synthesis of chalcones and 2-pyrazoline derivatives has been an active field of research due to the established pharmacological effects of these compounds. In this study, a series of chalcone (1a-i), 2-pyrazoline-1-carbothioamides (2a-i), and 2-pyrazoline

Synthesis and anticancer activity of 1,3,5-triaryl-1H-pyrazole

Previous studies demonstrated that some pyrazole derivatives could be considered as potential anticancer agents. A series of 1,3,5-triaryl-1H-pyrazole derivatives were prepared by the reaction of phenylhydrazin and different chalcones. The previous classi

A 1H NMR Investigation Concerning the Insertion of Pyridinium N-Phenoxide Betaines into Micelles

The 1H NMR spectra of pyridinium N-phenoxide betaines are clarified by means of doubleresonance experiments and the spectra of chlorosubstituted derivatives of the betaines.The spectra have been investigated in different mixtures of solvents. - The interp