59959-74-9Relevant academic research and scientific papers
Reduction of Nitroarenes to Anilines in Basic Alcoholic Media
Prato, Maurizio,Quintily, Ugo,Scorrano, Gianfranco
, p. 1419 - 1424 (1986)
Substituted nitrobenzenes are reduced by alkoxide ions in alcohols to the corresponding azoxy and aniline derivatives.The reaction leading to anilines has been investigated in detail.Two different processes have been identified, both initiated by the condensation between the nitrosoarene intermediate (the first product of the reduction reaction) and the product of oxidation of the solvent.The imino derivative thus formed (ArN=CH-COR) may either undergo hydrolysis (to aniline) or form, through a series of redox processes, compounds containing the ArNH-CO moiety.These are also hydrolysed to anilines in a slower reaction.
Substrate-controlled and highly stereoselective synthesis of 2-aminobut-2-ene-1, 4-diones
Deng, Cong,Yang, Yan,Gao, Meng,Zhu, Yan-Ping,Wu, An-Xin,Ma, Jun-Rui,Yin, Guo-Dong
, p. 3828 - 3834 (2012/07/02)
2-Methylthio-substituted 1,4-enediones, obtained from readily available aryl methyl ketones, were reacted with primary or secondary amines to afford the desired 1,4-diaryl-2-aminobut-2-ene-1,4-diones in excellent yields with high Z/E-stereoselectivity.
Synthesis, Structure, and Reactivity of 1,4-Diaryl-2-(arylamino)but-2-ene-1,4-diones
Paradisi, Cristina,Prato, Maurizio,Quintily, Ugo,Scorrano, Gianfranco
, p. 5156 - 5159 (2007/10/02)
The one-pot synthesis of the title compounds (1) is achieved by reacting acetophenones and nitrobenzenes in 2-propanol with potassium 2-propoxide.The stereochemistry of the 2-butenes has been determined to be Z from an X-ray analysis.Hydrolysis and reaction with hydrazine are reported as examples of the reactivity of the title compounds.
