59961-00-1

Basic information

• Product Name: 6-broMo-2-Methyl-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 6-broMo-2-Methyl-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 59961-00-1
• Molecular Formula: C10H12BrN
• Molecular Weight: 226.11298
• Mol File: 59961-00-1.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-broMo-2-Methyl-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-broMo-2-Methyl-1,2,3,4-tetrahydroisoquinoline(59961-00-1)
• EPA Substance Registry System: 6-broMo-2-Methyl-1,2,3,4-tetrahydroisoquinoline(59961-00-1)

Safety Data

• Hazardous Substances Data: 59961-00-1(Hazardous Substances Data)

Usage

General Description

6-bromo-2-methyl-1,2,3,4-tetrahydroisoquinoline is a chemical compound with the molecular formula C10H12BrN. It is a brominated derivative of tetrahydroisoquinoline, a class of organic compounds with a core structure comprised of a benzene ring fused to a saturated alicyclic ring. This chemical is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its potential as a building block for more complex molecules. It possesses biological activity and has been studied for its potential as an anti-inflammatory and analgesic agent. It is important to handle this compound with caution, as it may pose hazards to health and the environment.

Upstream product

• 50-00-0 formaldehyd 
• 226942-29-6 6-bromo-1,2,3,4-tetrahydroisoquinoline 
• 64-18-6 formic acid 
• 34784-05-9 6-bromo-isoquinoline 
• 913295-10-0 6-bromo-2-methylisoquinolinium triflate 

Downstream Products

• 922718-57-8 2-methyl-6-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

NAPHTHYRIDINE DERIVATIVES AS PRC2 INHIBITORS

Disclosed are compounds of formula (I) or (II) that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.

PRC2 INHIBITORS

The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention. (Formula (I))

RESORCINOL DERIVATIVE AS HSP90 INHIBITOR

The present invention relates to a compound represented by formula (I) of a resorcinol derivative as an HSP90 inhibitor or pharmaceutically accepted salts thereof. The compound in the present invention has the activity of inhibiting heat shock protein HSP90. Therefore, the compound in the present invention is used to treat proliferative diseases such as cancer and neurodegenerative diseases. The present invention further provides the compounds and preparation methods for pharmaceutical compositions comprising the compounds, a method for treating diseases, and pharmaceutical compositions comprising the compounds.