600-59-9 Usage
Uses
Used in Pharmaceutical Industry:
3-beta-hydroxy-5-alpha-pregnane-11,20-dione is used as a therapeutic agent for the treatment of various neurological and psychiatric disorders due to its mood-regulating, stress-reducing, and anxiety-relieving properties. It is particularly being explored for its potential in managing conditions such as depression, anxiety disorders, and post-traumatic stress disorder (PTSD).
Used in Neurodegenerative Disease Treatment:
In the field of neurology, 3-beta-hydroxy-5-alpha-pregnane-11,20-dione is considered for its potential role in treating chronic pain, traumatic brain injury, and neurodegenerative diseases. Its neuroprotective and neuroregenerative effects are currently under investigation to determine its full therapeutic potential.
Used in Research and Development:
3-beta-hydroxy-5-alpha-pregnane-11,20-dione is utilized in scientific research to further understand its mechanisms of action and explore additional therapeutic applications. Ongoing studies aim to elucidate its impact on the central nervous system and identify how it can be effectively harnessed for medical treatments.
While the potential applications of 3-beta-hydroxy-5-alpha-pregnane-11,20-dione are promising, it is important to note that further research is necessary to fully comprehend its mechanisms and establish its safety and efficacy in various clinical settings.
Check Digit Verification of cas no
The CAS Registry Mumber 600-59-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,0 and 0 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 600-59:
(5*6)+(4*0)+(3*0)+(2*5)+(1*9)=49
49 % 10 = 9
So 600-59-9 is a valid CAS Registry Number.
600-59-9Relevant academic research and scientific papers
NEUROACTIVE STEROIDS AND METHODS OF PREPARATION
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, (2020/01/31)
Disclosed are neuroactive steroid anaesthetic agents, methods for their preparation and compositions comprising the same. The invention provides scaled up and/or GMP methods for preparing neuroactive steroids, such as alfaxalone, alfadolone and alfadolone acetate.
Allopregnanolone and pregnanolone analogues modified in the C ring: Synthesis and activity
Slavíková, Barbora,Bujons, Jordi,Matyá?, Libor,Vidal, Miguel,Babot, Zoila,Kri?tofíková, Zdena,Su?ol, Cristina,Kasal, Alexander
, p. 2323 - 2336 (2013/06/04)
(25R)-3β-Hydroxy-5α-spirostan-12-one (hecogenin) and 11α-hydroxypregn-4-ene-3,20-dione (11α-hydroxyprogesterone) were used as starting materials for the synthesis of a series of 11- and 12-substituted derivatives of 5ξ-pregnanolone (3α-hydroxy-5α- pregnan-20-one and 3α-hydroxy-5β-pregnan-20-one), the principal neurosteroid acting via γ-aminobutyric acid (GABA). These analogues were designed to study the structural requirements of the corresponding GABA A receptor. Their biological activity was measured by in vitro test with [3H]flunitrazepam as radioligand in which allopregnanolone and its active analogues stimulated the binding to the GABAA receptor. Analysis of the SAR data suggests dependence of the flunitrazepam binding activity on the hydrophobic-hydrophilic balance of the groups at the C-ring edge rather than on specific interactions between them and the receptor.
