60027-87-4Relevant academic research and scientific papers
Zirconium-catalyzed Nagata reaction for the synthesis of 2-aryl-1,3,2-aryldioxaborins via a mild three-component condensation of phenols, aldehydes, and boronic acid
Zheng, Hongchao,Hall, Dennis G.
supporting information; experimental part, p. 4256 - 4259 (2010/09/07)
An efficient ZrCl4-catalyzed ortho-hydroxyalkylation of phenols with aldehydes promoted by 3,5-bis(trifluoromethyl)phenyl boronic acid, leading to the formation of 2-aryl-1,3,2-aryldioxaborins, was investigated and optimized. The reaction afforded the desired aryldioxaborins in good to excellent yields under mild conditions at room temperature. The electron-deficient boronic acid promoter was essential. Electron-rich phenols react faster, and both alkyl and aryl aldehydes are suitable substrates. The resulting aryldioxaborins can be further elaborated to produce substituted saligenols, 2-ethoxy chromans, and 2-substituted phenols.
A New Generation of o-Quinone Methides from o-(1-(Alkylthio)alkyl)phenols under Mild Conditions
Inoue, Tsutomu,Inoue, Seiichi,Sato, Kikumasa
, p. 653 - 656 (2007/10/02)
o-(1-(Alkylthio)alkyl)phenols are converted into o-quinone methides in good yield by treatment with silver oxide under mild conditions.Since the methides tend to prefer (E) configuration, cis-4-alkyl-2-alkoxychromans are exclusively obtained as a result o
o-QUINONE METHYDES 2. STEREOSELECTIVITY IN CYCLOADDITION REACTIONS OF o-QUINONE METHIDES WITH VINYL ETHERS.
Arduini, Arturo,Bosi, Anna,Pochini, Andrea,Ungaro, Rocco
, p. 3095 - 3104 (2007/10/02)
Cycloaddition reactions between vinyl ethers 3 and o-quinone methydes 2, thermally generated from 2-hydroxybenzyl alcohols 1, have been studied.The structure and conformational preferences of the 4-substituted 2-ethoxy-(2,3)-dihydro-2H-benzopyrans 4-9 obt
