60031-27-8

Basic information

• Product Name: methyl 2-(2-nitrobenzyl)propanoate
• Synonyms: methyl 2-(2-nitrobenzyl)propanoate
• CAS NO: 60031-27-8
• Molecular Weight: 223.229
• Mol File: 60031-27-8.mol

Chemical Properties

• CAS DataBase Reference: methyl 2-(2-nitrobenzyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-nitrobenzyl)propanoate(60031-27-8)
• EPA Substance Registry System: methyl 2-(2-nitrobenzyl)propanoate(60031-27-8)

Safety Data

• Hazardous Substances Data: 60031-27-8(Hazardous Substances Data)

Upstream product

• 31469-15-5 1-methoxy-2-methyl-1-trimethylsiloxy-1-propene 
• 577-19-5 2-nitrophenyl bromide 

Downstream Products

• 31883-79-1 3-methyl-3,4-dihydroquinolin-2(1H)-one 

Relevant articles and documents

Palladium-catalyzed β-arylation of silyl ketene acetals and application to the synthesis of benzo-fused δ-lactones

Silyl ketene acetals are shown to be competent nucleophiles in Pd-catalyzed migrative C(sp3)-H arylations. Compared to the parent ester lithium enolates, they possess decreased reactivity but enhanced chemoselectivity. This behavior was exploited through the synthesis of valuable benzo-fused δ-lactones such as 1-isochromanones and dihydrocoumarins.