6006-24-2

Upstream product

• 186581-53-3 diazomethane 
• 32399-48-7 cycloheptatriene-7-carbonyl chloride 
• 34733-74-9 bicyclo[4.2.1]nona-2,4,7-trien-9-one 
• 629-20-9 1,3,5,7-cyclooctatetraene 
• 25928-15-8 7-ethynyl-cyclohepta-1.3.5-triene 
• 27081-10-3 tropylium tetrafluoroborate 
• 34733-74-9 bicyclo<4.2.1>nona-2,4,7-triene-9-one 

Downstream Products

• 54549-58-5 9α-Formyl-barbaralan 
• 15719-09-2 tricyclo[3.3.2.0^2,8]deca-6,9-dien-4-one 
• 38368-89-7 C₂₂H₁₈O₂ 
• 127223-01-2 4-Hydroxy-8-(2,3,5,6-tetrachloro-4-hydroxy-phenoxy)-bicyclo[3.3.1]nona-2,6-dien-9-one 
• 127223-02-3 4-Methoxy-8-(2,3,5,6-tetrachloro-4-hydroxy-phenoxy)-bicyclo[3.3.1]nona-2,6-dien-9-one 
• 15677-13-1 Bicyclo<4.2.2>deca-2,4,7,9-tetraen 
• 36629-01-3 Bicyclo[4.2.2]deca-2.4.9-trien-7-on-tosylhydrazon 
• 15598-84-2 9-Phenyl-9-hydroxy-tricyclo<3.3.2.0^2,8>decadien-(3,6) 
• 283-50-1 Bicyclo<3.3.2>decane 
• 127222-97-3 C₂₄H₁₆N₂O₂ 

Relevant academic research and scientific papers

Synthesis of Barbaralones and Bullvalenes Made Easy by Gold Catalysis

The gold(I)-catalyzed oxidative cyclization of 7-ethynyl-1,3,5-cycloheptatrienes gives 1-substituted barbaralones in a general manner, which simplifies the access to other fluxional molecules. As an example, we report the shortest syntheses of bullvalene, phenylbullvalene, and disubstituted bullvalenes, and a readily accessible route to complex cage-type structures by further gold(I)-catalyzed reactions.

BRIDGED POLYCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS

The invention is directed to amides of bicyclic amine compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

Structural Fluxionality in the Tricyclo2,8>nona-3,6-dienyl and Bicyclonona-2,6,8-trienyl Radicals

E.s.r observation of radicals derived from 9-bromtricyclo2,8>nona-3,6-diene, and related compounds, showed that they rearrange by β-scission to bicyclonona-2,6,8-trienyl radicals extremly rapidly; the latter radicals have hyperfine splittings similar to those of allyl radicals. 9-Deuterio- and 2-deuterio-9-bromotricyclo2,8>nona-3,6-diene were reduced with tributyltin hydride.The pattern of deuterium scrambling in the bicyclonona-2,6,8-triene and tricyclo2,8>nona-3,6-diene products showed that the intermediate radicals take part in a degenerate rearrangement sequence which makes them fully fluxional in three dimensions.The two radicals are in equilibrium at ca. 375 K, but the bicyclotrienyl species is more important by a factor of ca. 102.Neither the experimental results nor MNDO semiempirical calculations provided any evidence of additional thermodynamic stabilisation in the radical pair beyond that expected for allyl delocalisation.