600725-75-5Relevant academic research and scientific papers
Synthesis and conformational analysis of Substance P antagonist analogues based on a 1,7-naphthyridine scaffold
Rombouts, Frederik J.R.,Van Den Bossche, Jeroen,Toppet, Suzanne M.,Compernolle, Frans,Hoornaert, Georges J.
, p. 4721 - 4731 (2003)
Two analogues of formerly described piperidine-based Substance P antagonists have been synthesised using an intramolecular Diels-Alder reaction of 1-(4-pentenyl)-3-phenyl-2(1H)-pyrazinones, followed by acidic methanolysis of the strained adducts to form t
