Tetrahedron p. 4721 - 4731 (2003)
Update date:2022-08-04
Topics:
Rombouts, Frederik J.R.
Van Den Bossche, Jeroen
Toppet, Suzanne M.
Compernolle, Frans
Hoornaert, Georges J.
Two analogues of formerly described piperidine-based Substance P antagonists have been synthesised using an intramolecular Diels-Alder reaction of 1-(4-pentenyl)-3-phenyl-2(1H)-pyrazinones, followed by acidic methanolysis of the strained adducts to form t
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