60083-36-5Relevant academic research and scientific papers
Copper(II)-Catalyzed Four-Component Oxysulfonylation/Diazenylation: Synthesis of α-Arylhydrazo-β-keto Sulfones
Gao, Wen-Chao,Cheng, Yu-Fei,Shang, Yu-Zhu,Chang, Hong-Hong,Li, Xing,Zhou, Rong,Qiao, Yan,Wei, Wen-Long
, p. 11956 - 11962 (2018)
A new and convenient method for one-pot synthesis of α-arylhydrazo-β-keto sulfones is developed via Cu (II)-catalyzed oxysulfonylation/diazenylation of alkenes. This four-component cascade reaction enables a series of α-arylhydrazo-β-keto sulfone derivatives accessed from readily available alkenes, sulfinates, and diazonium salts under aerobic conditions. Furthermore, the 3-sulfonyl cinnolin-4(1H)-one skeleton is successfully constructed from the corresponding α-arylhydrazo-β-keto sulfone product under basic conditions.
