60093-30-3

Basic information

• Product Name: Thiourea, N-cyano-N'-phenyl-, monosodium salt
• CAS NO: 60093-30-3
• Molecular Formula: C8H7N3S.Na
• Molecular Weight: 199.212
• Mol File: 60093-30-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thiourea, N-cyano-N'-phenyl-, monosodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N-cyano-N'-phenyl-, monosodium salt(60093-30-3)
• EPA Substance Registry System: Thiourea, N-cyano-N'-phenyl-, monosodium salt(60093-30-3)

Safety Data

• Hazardous Substances Data: 60093-30-3(Hazardous Substances Data)

Upstream product

• 420-04-2 CYANAMID 
• 103-72-0 phenyl isothiocyanate 

Downstream Products

• 67944-70-1 (2-cyanoimino-3-phenyl-thiazolidin-4-yl)-acetonitrile 
• 907961-82-4 3-(4-amino-2-(phenylamino)thiazole-5-carbonyl)-2H-chromen-2-one 
• 197847-18-0 ethyl 4-amino-2-(phenylamino)thiazole-5-carboxylate 
• 13807-14-2 1-(4-amino-2-(phenylamino)thiazol-5-yl)ethanone 
• 67967-98-0 (2-cyanoimino-3-phenyl-thiazolidin-4-yl)-acetic acid ethyl ester 
• 67944-69-8 (2-cyanoimino-3-phenyl-thiazolidin-4-yl)-acetic acid methyl ester 
• 32086-71-8 1-(4-oxo-4H-benzo[e][1,3]thiazin-2-yl)-3-phenyl-thiourea 
• 4552-25-4 1-(4-oxo-4,5-dihydro-thiazol-2-yl)-3-phenyl-thiourea 
• 32086-42-3 1-(1,5-dioxo-5,6-dihydro-1H-[1,3]thiazino[6,5-c]quinolin-3-yl)-3-phenyl-thiourea 
• 896-13-9 [4-oxo-2-(3-phenyl-thioureido)-4,5-dihydro-thiazol-5-yl]-acetic acid 
• 112178-66-2 3-Brom-5-(p-bromanilino)-1,2,4-thiadiazol 

Relevant articles and documents

Synthesis and biological evaluation of new coumarins bearing 2,4-diaminothiazole-5-carbonyl moiety

A series of new coumarin-containing compounds 3a-l and 4a-c was designed and synthesized based on the chalcone-type 4-amino-5-cinnamoylthiazole scaffold 2, and screened for their in vitro anticancer and antioxidant activities. Representatively, the 2-thiomorpholinothiazole derivative 3k with IC50 values of 7.5–16.9 μg/ml demonstrated good cytotoxic effects against tested cell lines MCF-7, HepG2 and SW480. Further investigation by flow cytometric analysis confirmed that this compound induces apoptotic cell death in MCF-7 cells and cause G1-phase arrest in the cell cycle. Moreover, most of compounds had intrinsic potential for radical scavenging activity and ferric-reducing power as investigated by DPPH and FRAP assays.