60116-82-7Relevant academic research and scientific papers
Facile oxidation of electron-poor benzo[b]thiophenes to the corresponding sulfones with an aqueous solution of H2O2 and P 2O5
Antonow, Dyeison,Marrafa, Teresa,Dawood, Irfaan,Ahmed, Tauheed,Haque, Mohammad R.,Thurston, David E.,Zinzalla, Giovanna
supporting information; experimental part, p. 2289 - 2291 (2010/07/08)
A facile oxidation for the clean conversion of benzo[b]thiophenes to their corresponding sulfones is described employing an aqueous solution of H 2O2 and P2O5; the solution can be prepared and stored on a multi-
N-LITHIO-N-(2-LITHIOETHYL)- AND N-LITHIO-N-(3-LITHIOPROPYL)-BENZAMIDE: DIRECT PREPARATION AND SYNTHETIC APPLICATIONS OF 2-LITHIOETHYL- AND 3-LITHIOPROPYL-AMINE EQUIVALENTS
Barluenga, Jose,Foubelo, Francisco,Fananas, Francisco J.,Yus, Miguel
, p. 2183 - 2192 (2007/10/02)
The successive reaction of 2-chloroethyl and 3-chloropropyl-benzamide with n-butyl-lithium and lithium naphthalenide at temperatures ranging between -78 and -50 deg C leads to N-lithio-N-(2-lithioethyl)- and N-lithio-N-(3-lithiopropyl)benzamide , which by treatment with different electrophiles (H2O, D2O, Me2S2, CO2, PriCHO, PhCHO, Me2CO, Ph2CO, and O2) yields the expected functionalized benzamides .The acidic and basic hydrolysis of compounds (10) and (11) gives different results depending on the structure of the substrate and the reaction conditions.
N-LITHIO-N-(2-LITHIOETHYL)BENZAMIDE: DIRECT PREPARATION OF A 2-LITHIOETHYLAMINE EQUIVALENT
Barluenga, Jose,Foubelo, Francisco,Fananas, Francisco J.,Yus, Miguel
, p. 2859 - 2860 (2007/10/02)
The successive reaction of 2-chloroethylbenzamide with n-butyl-lithium and lithium naphthalenide at -78 deg C leads to N-lithio-N-(2-lithioethyl)benzamide, which reacts with different electrophiles (H2O, D2O, Me2S2, CO2, i-PrCHO, PhCHO, Me2CO, Ph2CO) to afford the expected 2-functionalized benzamides.
