60134-71-6

Usage

Uses

Nocardicin B is a β-lactam antibiotic.

InChI:InChI=1/C23H24N4O9/c24-16(22(31)32)9-10-36-15-7-3-12(4-8-15)18(26-35)20(29)25-17-11-27(21(17)30)19(23(33)34)13-1-5-14(28)6-2-13/h1-8,16-17,19,28,35H,9-11,24H2,(H,25,29)(H,31,32)(H,33,34)/b26-18+/t16-,17+,19-/m1/s1

Upstream product

• 123004-77-3 (R)-4-[4-((R)-Amino-{(S)-1-[(R)-tert-butoxycarbonyl-(4-hydroxy-phenyl)-methyl]-2-oxo-azetidin-3-ylcarbamoyl}-methyl)-phenoxy]-2-tert-butoxycarbonylamino-butyric acid tert-butyl ester; hydrochloride 
• 123004-76-2 (R)-4-[4-((R)-Benzyloxycarbonylamino-{(S)-1-[(R)-tert-butoxycarbonyl-(4-hydroxy-phenyl)-methyl]-2-oxo-azetidin-3-ylcarbamoyl}-methyl)-phenoxy]-2-tert-butoxycarbonylamino-butyric acid tert-butyl ester 
• 111216-46-7 tert-butyl N-(4,5-diphenyl-4-oxazolin-2-onyl)-L-seryl-D-glycinate 
• 110207-46-0 (-)-3-N-(4,5-diphenyl-4-oxazolin-2-onyl)aminocardicinic acid tert-butyl ester 
• 123004-75-1 D-N-(benzyloxycarbonyl)-2-<4--3-(tert-butoxycarbonyl)propoxy>phenyl>glycine 
• 123004-73-9 (-)-tert-butyl 3-aminonocardicinate hydrochloride 
• 26787-75-7 (R)-2-(((benzyloxy)carbonyl)amino)-2-(4-hydroxyphenyl)acetic acid 
• 63598-46-9 3-<2-(4-hydroxyphenyl)-2-(hydroxyimino)acetamido>nocardicinic acid 
• 110269-45-9 di-tert-butyl N-(tert-butoxycarbonyl)nocardicin A 
• 88147-49-3 diphenylmethyl (αR,3S)-3-azido-α--2-oxo-1-azetidineacetate 
• 88147-46-0 (3S)-α-<(p-benzyloxy)phenyl>-N-(diphenylmethyl)-3-hydroxy-2-oxo-1-azedineacetamide 
• 73888-92-3 diphenylmethyl D-4-(p-acetylphenoxy)-2-(1-t-butoxyformamido)butyrate 
• 88147-53-9 4-Chloro-benzenesulfonic acid (R)-1-[(benzhydryl-carbamoyl)-(4-benzyloxy-phenyl)-methyl]-2-oxo-azetidin-3-yl ester 
• 88147-50-6 (αR,3S)-3-amino-α-(p-hydroxyphenyl)-2-oxo1-azetidine-acetic acid Na salt 

Downstream Products

• 73888-88-7 N,O-Bis(t-butoxycarbonyl)-3-amino-nocardicinsaure 
• 73888-86-5 N,O-Bis(t-butoxycarbonyl)-3-amino-nocardicinsaure-(diphenylmethyl)ester 
• 73888-84-3 N-(t-Butoxycarbonyl)-3-amino-nocardicinsaure 
• 67509-41-5 3-aminonocardicinic acid hydrochloride 

Relevant academic research and scientific papers

Total syntheses of (-)-nocardicins A-G: A biogenetic approach

The known nocardicins A-G have been synthesized, several for the first time, having geometric and stereoisomeric purities of a high order. The syntheses proceed through the central intermediacy of tert-butyl (-)-3-aminocardicinate (14), which has been pre

A total synthesis of nocardicins

Four-component-condensation of D-isoserine or L-isoserine, diphenylmethyl isocyanide and p-(benzyloxy)benzaldehyde was used to construct a functionalized β-lactam ring system which was transformed in 4 steps into 3-aminocardicinic acid. A protected side c