60135-00-4

Upstream product

• 100-52-7 benzaldehyde 
• 105-45-3 acetoacetic acid methyl ester 
• 2538-76-3 1,1'-benzylidenedipiperidine 

Downstream Products

• 5337-88-2 3-methyl-5-phenyl-2-cyclohexen-1-one 
• 1258974-95-6 methyl 2,3-dimethyl-4-oxo-6-phenyl-2-cyclohexenecarboxylate 
• 1316834-14-6 C₁₅H₁₄O₄ 

Relevant academic research and scientific papers

The use of Hagemann's Esters to prepare highly functionalized phenols and benzenes

Hagemann's esters can be converted into highly functionalized phenols or arenes. The systematic functionalization of Hagemann's ester derivatives permits the preparation of tri-and tetraalkyl-substituted phenols or tetra-, penta-, and hexaalkyl-substituted benzenes. Kotnis's aromatization procedure was found to be solvent dependent, and Suzuki couplings were found to be sensitive to steric hindrance. Wittig olefination and ortho-Claisen reactions were reliable means to introduce alkyl substituents at C-4 and/or C-5 positions, respectively. The acid-promoted dehydration of tertiary alcohol 46 to produce enone 47, followed by its selective alkylation (cf. 48) is new. ARKAT USA, Inc.

Synthesis and structures of 6-aryl-1,5-dimethoxycarbonyl-2-methyl-4-morpholino-1,3-cyclohexadienes and related compounds

Reaction of benzaldehyde (1a) with methyl acetoacetate (2) in the presence of morpholine (or piperidine) and AcOH in refluxing C6H6 yielded a new condensation product, 1,5-dimethoxycarbonyl-2-methyl-4-morpholino (or piperidino)-6-phe

A Novel, One Pot Synthesis of 4-Carbalkoxy-3-methyl-5-substitutedphenyl-2-cyclohexen-1-ones

A novel, one pot synthesis of 4-carbalkoxy-3-methyl-5-substitudedphenyl-2-cyclohexen-1-ones (1-8) has been achieved by reacting appropriately substituted benzaldehyde with methyl or ethyl acetoacetate in presence of piperidine in ethanol.The structures (1