602310-67-8

Basic information

• Product Name: methyl 5-amino-3-methylthiophene-2-carboxylate
• Synonyms: 2-Thiophenecarboxylic acid, 5-amino-3-methyl-, methyl ester
• CAS NO: 602310-67-8
• Molecular Formula: C₇H₉NO₂S
• Molecular Weight: 171.2139
• Mol File: 602310-67-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 5-amino-3-methylthiophene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-amino-3-methylthiophene-2-carboxylate(602310-67-8)
• EPA Substance Registry System: methyl 5-amino-3-methylthiophene-2-carboxylate(602310-67-8)

Safety Data

• Hazardous Substances Data: 602310-67-8(Hazardous Substances Data)

Upstream product

• 81452-54-2 methyl 3-methylthiophene-2-carboxylate 
• 23806-24-8 3-methyl-2-thiophenecarboxylic acid 
• 372-09-8 cyanoacetic acid 
• 105-45-3 acetoacetic acid methyl ester 
• 956118-35-7 3-methyl-5-nitro-thiophene-2-carboxylic acid methyl ester 

Relevant articles and documents

AMIDE DERIVATIVE

The present invention relates to a compound or a pharmacologically acceptable salt thereof that has an excellent antagonistic effect on a neurokinin NK1 receptor, a neurokinin NK2 receptor, and a muscarine M3 receptor and is useful as a therapeutic agent for bronchial asthma, chronic obstructive pulmonary disease, or the like. A compound represented by general formula (I): [wherein R1 represents a hydrogen atom, a C1-C6 alkyl group, or the like; R2 represents a hydrogen atom, a C1-C6 alkyl group, or the like; R3 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group A, or the like; R4 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group A, or the like; L1 represents a C1-C10 alkylene group or the like; L2 represents a carbonyl group, a group represneted by the formula -N(R5)-C(=O)-, a group represented by the formula -C(=O)-N(R5)-, or the like; R5 represents a hydrogen atom, a C1-C6 alkyl group, or the like; E represents a phenylene group that may be substituted with 1 to 4 group(s) independently selected from Substituent Group A, or the like; m is an integer of 1 to 4; n is an integer of 0 to 4; p is an integer of 0 to 2; q is an integer of 1 to 10; r is 1 or 2; s is 0 or 1; and Substituent Group A represents the group consisting of a halogen atom, a C1-C6 alkyl group, C1-C6 halogenated alkyl group, or the like] or a pharmacologically acceptable salt thereof.