60283-15-0Relevant articles and documents
Chemo- and Stereoselective Synthesis of Fluorinated Amino Alcohols through One-pot Reactions using Alcohol Dehydrogenases and Amine Transaminases
González-Martínez, Daniel,Gotor, Vicente,Gotor-Fernández, Vicente
supporting information, p. 5398 - 5410 (2020/10/06)
A series of amino alcohols have been prepared in a chemo-, diastereo- and enantioselective fashion starting from the corresponding (het)aryl diketones, avoiding tedious chemical protection and deprotection steps. Different alcohol dehydrogenases have been
Chemoselective reduction of ketones: Trifluoromethylketones versus methylketones
Sasaki, Shigeru,Yamauchi, Takayasu,Kubo, Hajime,Kanai, Masatomi,Ishii, Akihiro,Higashiyama, Kimio
, p. 1497 - 1500 (2007/10/03)
Treatment of an equimolar mixture of trifluoromethylketones (TFMKs) and methylketones (MKs) with Et2Zn resulted in selective reduction of the TFMKs in good yield. In contrast, treatment of an equimolar mixture of TFMKs and MKs with NaBH4 in the presence of CeCl3 in EtOH/H 2O (10:1) at -10°C reduced only the MKs.