60285-80-5

Basic information

• Product Name: Phenol, 2,6-bis(1,1-dimethylethyl)-4-[(phenylsulfonyl)methyl]-
• CAS NO: 60285-80-5
• Molecular Formula: C21H28O3S
• Molecular Weight: 360.518
• Mol File: 60285-80-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phenol, 2,6-bis(1,1-dimethylethyl)-4-[(phenylsulfonyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,6-bis(1,1-dimethylethyl)-4-[(phenylsulfonyl)methyl]-(60285-80-5)
• EPA Substance Registry System: Phenol, 2,6-bis(1,1-dimethylethyl)-4-[(phenylsulfonyl)methyl]-(60285-80-5)

Safety Data

• Hazardous Substances Data: 60285-80-5(Hazardous Substances Data)

Upstream product

• 128-37-0 2,6-di-tert-butyl-4-methyl-phenol 
• 66-99-9 β-naphthaldehyde 
• 88-26-6 3,5-di-tert-butyl-4-hydroxybenzyl alcohol 
• 873-55-2 sodium benzenesulfonate 
• 623-73-4 diazoacetic acid ethyl ester 

Relevant articles and documents

Electrochemical Radical δ-H Sulfonylation Reaction for the Synthesis of 4-((Aryl,Arylsul fonyl)methylene)-2,5-Cyclohexadiene Derivatives

A novel and efficient electrochemical radical δ-H sulfonylation reaction of para-quinone methides (p-QMs) and sodium sulfinates has been achieved under common laboratory conditions. In this strategy, a new C(sp2)-S bond was constructed for the synthesis of 4-((aryl,arylsulfonyl)methylene)-2,5-cyclohexadiene derivatives with a broad substrate scope, good functional group tolerance, and mild conditions. Further studies showed that the reaction had an excellent regional selectivity.

Cross coupling of sulfonyl radicals with silver-based carbenes: A simple approach to β-carbonyl arylsulfones

A coupling reaction between sulfonyl radicals and silver-based carbenes has been well established. This simple radical-carbene coupling (RCC) process provided an efficient approach to a variety of β-carbonyl arylsulfones from sodium arylsulfinates and diazo compounds, and was characterized by wide substrate scope, easy scale-up, simple manipulation, accessible starting materials, and mild reaction conditions.

Iodide/tert-Butyl Hydroperoxide-Mediated Benzylic C–H Sulfonylation and Peroxidation of Phenol Derivatives

We disclose here the first iodine/tert-butyl hydroperoxide (I2/TBHP)-mediated benzylic C–H sulfonylation of phenol derivatives. This new methodology provides an economic, operationally simple and metal-free approach toward C(sp3)–S bond formation with medium to excellent yields at room temperature. Moreover, a novel sulfonylative and peroxidative bifunctionalization of phenol derivatives was also achieved by changing the amount of the oxidant. The reaction mechanism is exemplified via a radical pathway. (Figure presented.).