60324-96-1

Basic information

• Product Name: Guanosine, N-benzoyl-2'-O-(tetrahydro-2H-pyran-2-yl)-
• CAS NO: 60324-96-1
• Molecular Formula: C22H25N5O7
• Molecular Weight: 471.47
• Mol File: 60324-96-1.mol

Chemical Properties

• CAS DataBase Reference: Guanosine, N-benzoyl-2'-O-(tetrahydro-2H-pyran-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Guanosine, N-benzoyl-2'-O-(tetrahydro-2H-pyran-2-yl)-(60324-96-1)
• EPA Substance Registry System: Guanosine, N-benzoyl-2'-O-(tetrahydro-2H-pyran-2-yl)-(60324-96-1)

Safety Data

• Hazardous Substances Data: 60324-96-1(Hazardous Substances Data)

Upstream product

• 118-00-3 G 
• 98-88-4 benzoyl chloride 
• 28288-50-8 N²,O^2',O^3',O^5'-tetrabenzoylguanosine 
• 3676-72-0 N²-benzoylguanosine 
• 78842-00-9 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-N²-benzoylguanosine 
• 110-87-2 3,4-dihydro-2H-pyran 
• 87125-05-1 2-N-benzoyl-2'-O-tetrahydropyranyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine 

Downstream Products

• 83416-90-4 C₅₅H₄₂Cl₄N₈O₁₃P₂ 
• 83416-91-5 C₄₉H₃₉Cl₃N₈O₁₃P₂ 
• 87125-07-3 2-N-benzoyl-2'-O-tetrahydropyranyl-5'-O-dimethoxytritylguanosine-3'-(p-chlorophenyl-2-cyanoethyl)phosphate 
• 87125-14-2 Phosphoric acid (2R,3R,4R,5R)-5-(2-benzoylamino-6-oxo-1,6-dihydro-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 
• 97626-10-3 Phosphoric acid (2R,3R,4R,5R)-5-(2-benzoylamino-6-oxo-1,6-dihydro-purin-9-yl)-2-hydroxymethyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 2-cyano-ethyl ester 
• 79970-27-7 5'-O-(methoxytrityl)-2'-O-(tetrahydropyranyl)-N²-benzoylguanosine 
• 83416-87-9 Phosphoric acid (2R,3R,4R,5R)-5-(2-benzoylamino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-2-ylmethyl ester bis-(5-chloro-quinolin-8-yl) ester 
• 71933-62-5 5'-O-(dimethoxytrityl)-2'-O-(tetrahydropyranyl)-N²-benzoylguanosine 

Relevant articles and documents

Synthesis of guanosine-3′-(5-bromo-4-chloroindol-3-YL)-phosphate (G-3′-BCIP)

N-2-Benzoyl-5′-O-dimethoxytrityl-2′-O- tetrahydropyranylguaaosine (5) and 1-acetyl-5-bromo-4-chloroindol-3-yl-3-phosphorodichloridate (7) were synthesized and coupled to give the title compound 9.

Application of the Tetraisopropyldisiloxane-1,3-diyl Group in the Chemical Synthesis of Oligoribonucleotides

The application of the tetraisopropyldisiloxane-1,3-diyl (TIPDSi) group for the large-scale preparation of the key components for the chemical synthesis of oligoribonucleotides by the triester approach is described. The key components, N-benzol-2'-O-tetra