60442-57-1Relevant articles and documents
Exploiting drug-resistant enzymes as tools to identify thienopyrimidinone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H
Masaoka, Takashi,Chung, Suhman,Caboni, Pierluigi,Rausch, Jason W.,Wilson, Jennifer A.,Taskent-Sezgin, Humeyra,Beutler, John A.,Tocco, Graziella,Le Grice, Stuart F. J.
supporting information, p. 5436 - 5445 (2013/07/26)
The thienopyrimidinone 5,6-dimethyl-2-(4-nitrophenyl)thieno[2,3-d] pyrimidin-4(3H)-one (DNTP) occupies the interface between the p66 ribonuclease H (RNase H) domain and p51 thumb of human immunodeficiency virus reverse transcriptase (HIV RT), thereby indu
Iodine catalysed synthesis and antibacterial evaluation of thieno-[2,3-d]pyrimidine derivatives
Bakavoli, Mehdi,Bagherzadeh, Ghodsieh,Vaseghifar, Maryam,Shiri, Ali,Pordeli, Parvaneh
experimental part, p. 653 - 655 (2010/03/24)
A new route via iodine catalysed heterocyclisation of 2-amino-4,5- dimethylthiophene-3-carboxamide with aromatic aldehydes affording a series of thieno[2,3-d]pyrimidine derivatives in a single step have been developed. Some of these compounds exhibited an