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2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE is a chemical compound characterized by the molecular formula C8H11N3OS. It is a thiophene ring derivative that features an amide functional group and a tertiary amine group. 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE is recognized for its role in organic synthesis and pharmaceutical research, where it serves as a building block for creating a variety of biologically active molecules. Its potential antibacterial and antifungal properties highlight its significance in the development of new drugs and pharmaceuticals. Furthermore, 2-amino-4,5-dimethylthiophene-3-carboxamide has demonstrated its utility in the production of agrochemicals and materials science applications, showcasing its versatility across different industries.

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  • 51486-04-5 Structure
  • Basic information

    1. Product Name: 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE
    2. Synonyms: TIMTEC-BB SBB000163;ART-CHEM-BB B000687;2-AMINO-4,5-DIMETHYL-3-THIOPHENECARBOXAMIDE;2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE;2-AMINO-4,5-DIMETHYL-THIOPHENE-3-CARBOXYLIC ACID AMIDE;AKOS MSC-0461;AKOS BB/0054;AKOS B000687
    3. CAS NO:51486-04-5
    4. Molecular Formula: C7H10N2OS
    5. Molecular Weight: 170.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 51486-04-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 252.1 °C at 760 mmHg
    3. Flash Point: 106.3 °C
    4. Appearance: /
    5. Density: 1.285 g/cm3
    6. Vapor Pressure: 0.0197mmHg at 25°C
    7. Refractive Index: 1.635
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE(51486-04-5)
    12. EPA Substance Registry System: 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE(51486-04-5)
  • Safety Data

    1. Hazard Codes: Xi,Xn
    2. Statements: 22
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 51486-04-5(Hazardous Substances Data)

51486-04-5 Usage

Uses

Used in Pharmaceutical Research:
2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE is used as a building block in the synthesis of biologically active molecules for pharmaceutical research. Its unique structure and functional groups contribute to the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE is utilized as a key intermediate for the preparation of various organic compounds. Its presence in the synthesis process allows for the creation of a wide range of chemical entities with diverse properties and uses.
Used in Agrochemical Production:
2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE is used as an ingredient in the production of agrochemicals. Its potential antibacterial and antifungal properties make it a valuable component in the development of pesticides and other agricultural chemicals aimed at protecting crops and enhancing yield.
Used in Materials Science:
In materials science, 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE is employed in the development of new materials with specific properties. Its incorporation into material formulations can lead to advancements in areas such as polymer science, where it may contribute to the creation of materials with improved characteristics for various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 51486-04-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,4,8 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 51486-04:
(7*5)+(6*1)+(5*4)+(4*8)+(3*6)+(2*0)+(1*4)=115
115 % 10 = 5
So 51486-04-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2OS/c1-3-4(2)11-7(9)5(3)6(8)10/h9H2,1-2H3,(H2,8,10)

51486-04-5 Well-known Company Product Price

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  • Aldrich

  • (CBR00080)  2-Amino-4,5-dimethylthiophene-3-carboxamide  AldrichCPR

  • 51486-04-5

  • CBR00080-1G

  • 3,221.01CNY

  • Detail

51486-04-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE

1.2 Other means of identification

Product number -
Other names F1973-0019

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51486-04-5 SDS

51486-04-5Relevant articles and documents

Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase

Massari, Serena,Bertagnin, Chiara,Pismataro, Maria Chiara,Donnadio, Anna,Nannetti, Giulio,Felicetti, Tommaso,Di Bona, Stefano,Nizi, Maria Giulia,Tensi, Leonardo,Manfroni, Giuseppe,Loza, Maria Isabel,Sabatini, Stefano,Cecchetti, Violetta,Brea, Jose,Goracci, Laura,Loregian, Arianna,Tabarrini, Oriana

, (2020/10/27)

Influenza viruses (Flu) are responsible for seasonal epidemics causing high rates of morbidity, which can dramatically increase during severe pandemic outbreaks. Antiviral drugs are an indispensable weapon to treat infected people and reduce the impact on

Exploiting drug-resistant enzymes as tools to identify thienopyrimidinone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H

Masaoka, Takashi,Chung, Suhman,Caboni, Pierluigi,Rausch, Jason W.,Wilson, Jennifer A.,Taskent-Sezgin, Humeyra,Beutler, John A.,Tocco, Graziella,Le Grice, Stuart F. J.

supporting information, p. 5436 - 5445 (2013/07/26)

The thienopyrimidinone 5,6-dimethyl-2-(4-nitrophenyl)thieno[2,3-d] pyrimidin-4(3H)-one (DNTP) occupies the interface between the p66 ribonuclease H (RNase H) domain and p51 thumb of human immunodeficiency virus reverse transcriptase (HIV RT), thereby indu

A novel series of positive modulators of the AMPA receptor: Discovery and structure based hit-to-lead studies

Jamieson, Craig,Basten, Stephanie,Campbell, Robert A.,Cumming, Iain A.,Gillen, Kevin J.,Gillespie, Jonathan,Kazemier, Bert,Kiczun, Michael,Lamont, Yvonne,Lyons, Amanda J.,MacLean, John K.F.,Moir, Elizabeth M.,Morrow, John A.,Papakosta, Marianthi,Rankovic, Zoran,Smith, Lynn

scheme or table, p. 5753 - 5756 (2010/12/18)

Starting from an HTS derived hit 1, application of biostructural data facilitated rapid optimization to lead 22, a novel AMPA receptor modulator. This is the first demonstration of how structure based drug design can be exploited in an optimization program for a glutamate receptor.

Iodine catalysed synthesis and antibacterial evaluation of thieno-[2,3-d]pyrimidine derivatives

Bakavoli, Mehdi,Bagherzadeh, Ghodsieh,Vaseghifar, Maryam,Shiri, Ali,Pordeli, Parvaneh

experimental part, p. 653 - 655 (2010/03/24)

A new route via iodine catalysed heterocyclisation of 2-amino-4,5- dimethylthiophene-3-carboxamide with aromatic aldehydes affording a series of thieno[2,3-d]pyrimidine derivatives in a single step have been developed. Some of these compounds exhibited an

PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS

-

Page/Page column 46, (2008/06/13)

The present invention relates to a heterocyclic derivative according to Formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceuti

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