60444-92-0

Basic information

• Product Name: 2-N-BUTOXYBENZAMIDE
• Synonyms: 2-butoxy-benzoic acid amide;H.P. 165;o-Butoxybenzamide;2-n-Butoxybenzamide;2-Butoxy-benzoesaeure-amid;BENZAMIDE,o-BUTOXY
• CAS NO: 60444-92-0
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.246
• Mol File: 60444-92-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 329.46°C (rough estimate)
• Density: 1.0945 (rough estimate)
• Refractive Index: 1.5080 (estimate)
• CAS DataBase Reference: 2-N-BUTOXYBENZAMIDE (CAS DataBase Reference)
• NIST Chemistry Reference: 2-N-BUTOXYBENZAMIDE (60444-92-0)
• EPA Substance Registry System: 2-N-BUTOXYBENZAMIDE (60444-92-0)

Safety Data

• Safety Statements: Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOsub xmlns="">x/sub>. See also a target="_blank" href="lom/card_sa.tes?href=content/sax0001/sdp00975.xml&view=print">AMIDES/a>.
• Hazardous Substances Data: 60444-92-0(Hazardous Substances Data)

Upstream product

• 17436-52-1 benzoyliminotriphenylphosphorane 
• 71-36-3 butan-1-ol 
• 445-28-3 2-fluorobenzamide 
• 4001-73-4 2-Bromobenzamide 
• 109-65-9 1-bromo-butane 
• 65-45-2 salicylamide 

Downstream Products

• 6609-59-2 2-butoxybenzonitrile 
• 139632-45-4 1-(2-Butoxy-benzoyl)-3-((1R,3R,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-urea 

Relevant articles and documents

Copper-Catalyzed Self-Condensation of Benzamide: Domino Reactions towards Quinazolinones

We herein report a simple and highly efficient microwave-assisted, copper-catalyzed and ligand-free synthetic method for 2-substituted 4(3H)-quinazolinones as domino reaction. This reaction proceeds via self-condensation of substrate (2-bromo/iodo benzamide) in the presence of a strong base and copper catalyst. The substituted quinazolinones were obtained in one-pot reaction by intramolecular cyclization (condensation) via Ullmann–type intermediate. Both the intermediates and quinazolinones were obtained in good yield and can be further used as building blocks for developing the potential novel drug-like compounds.