17436-52-1

Upstream product

• 93-89-0 benzoic acid ethyl ester 
• 13916-35-3 lithium triphenylphosphonium azayldiide 
• 53170-70-0 C₂₆H₂₂NOP 
• 4461-33-0 benzoyl isocyanate 
• 15931-69-8 bromure de triphenyl aminophosphonium 
• 495-18-1 Benzohydroxamic acid 
• 74-88-4 methyl iodide 
• 951654-95-8 N-(5λ⁴-dibenzo[b,d]thiophen-5-ylidene)benzamide 
• 603-35-0 triphenylphosphine 
• 15729-44-9 amino(triphenyl)phosphonium chloride 
• 2240-47-3 imino(triphenyl)phosphorane 
• 582-61-6 benzoyl azide 
• 98-88-4 benzoyl chloride 
• 611-74-5 N,N-dimethylbenzamide 

Downstream Products

• 100-47-0 benzonitrile 
• 791-28-6 Triphenylphosphine oxide 
• 87112-12-7 Ni(C₆H₅)((C₆H₅)3P)((C₆H₅)2PNC(C₆H₅)O) 
• 1338230-09-3 (2-(diphenylphosphoryl)phenyl)(phenyl)methanone 
• 1224428-85-6 AuCl₂(2-C₆H₄C(O)NPPh₃)-CH₂Cl₂(1/1) 
• 50620-99-0 alpha-cyanocinnamic acid ethyl ester 
• 57076-07-0 2-isobutoxybenzamide 
• 60444-92-0 2-butoxybenzamide 
• 63920-58-1 2-isopropoxybenzamide 
• 59643-84-4 2-n-propoxybenzamide 
• 93119-96-1 3,4-diphenyl-2H-isoquinolin-1-one 
• 1253388-35-0 5,6,13-triphenyl-8H-isoquinolino[3,2-a]isoquinolin-8-one 
• 86155-81-9 trichloro(benzonitrile)bis(triphenylphosphine)osmium(III) 
• 86155-76-2 dichloro(N-benzoyltriphenylphosphinimine)bis(triphenylphosphine)osmium(II) 

Relevant academic research and scientific papers

Interweaving Visible-Light and Iron Catalysis for Nitrene Formation and Transformation with Dioxazolones

Herein, visible-light-driven iron-catalyzed nitrene transfer reactions with dioxazolones for intermolecular C(sp3)-N, N=S, and N=P bond formation are described. These reactions occur with exogenous-ligand-free process and feature satisfactory to excellent yields (up to 99 %), an ample substrate scope (109 examples) under mild reaction conditions. In contrast to intramolecular C?H amidations strategies, an intermolecular regioselective C?H amidation via visible-light-induced nitrene transfer reactions is devised. Mechanistic studies indicate that the reaction proceeds via a radical pathway. Computational studies show that the decarboxylation of dioxazolone depends on the conversion of ground sextet state dioxazolone-bounding iron species to quartet spin state via visible-light irradiation.

Method for synthesizing phosphinimide compound

The invention relates to a method for synthesizing a phosphonimide compound, and belongs to the field of metal catalytic organic synthesis. The method for synthesizing the phosphonimide compound comprises the following steps: adding an N-hydrocarbon acyloxy amide derivative, tertiary phosphine, a catalyst and an organic solvent into a reaction container, carrying out a reaction at a room temperature in an air atmosphere, and after the reaction is completed, carrying out post-treatment so as to obtain the phosphinimide compound. The method for synthesizing the phosphonimide compound disclosed by the invention has the following beneficial effects: (1) the range of a substrate is wide; (2) the catalyst is relatively low in price and less in usage amount; (3) the reaction operation is simple;and (4) the reaction yield is high, and high yield can still be obtained when the reaction is amplified to a gram level.

Novel method for constructing nitrogen-phosphorus double bonds through visible light catalysis

The invention belongs to the technical field of medical and natural compound chemical intermediates and related chemistry, and relates to a novel method for constructing nitrogen-phosphorus double bonds through visible light catalysis. According to the in

Preparation method of iron-catalyzed phosphazene compound

The invention belongs to the field of pharmaceutical and natural compound chemical intermediates and related chemical technologies, and relates to a preparation method of an iron-catalyzed phosphazenecompound. The preparation method comprises the steps th

Method for preparing ruthenium-catalyzed phosphoazene compound

The invention belongs to the technical field of pharmaceutical and natural compound chemical intermediates and related chemistry, and relates to a method for preparing a ruthenium-catalyzed phosphoazene compound. The method includes the step that the phos

Preparation method of phosphorus nitrene compound catalyzed by cadmium sulfide

The invention belongs to the technical field of medicine and natural compound chemical intermediate and related chemistry, and relates to a preparation method of a phosphorus nitrene compound catalyzed by cadmium sulfide. A phosphine compound and 3-substi

Unprecedented Transformation of a Directing Group Generated in Situ and Its Application in the One-Pot Synthesis of 2-Alkenyl Benzonitriles

An unprecedented protocol for the transformation of benzoyl azides into benzonitrile derivatives via iminophosphoranes generated in situ is described. The strategy was successfully applied to the de-novo synthesis of 2-alkenylated benzonitrile derivatives from benzoyl azides through ortho CH activation/alkenylation followed by subsequent rearrangement. The salient features of this protocol involve incorporation of two important functionalities through cyanation and olefination in one pot under mild reaction conditions by using a less expensive Ru catalyst. The mechanism was established by isolating and characterising (using 31PNMR) an intermediate with two ortho functionalities, iminophosphorane and olefin, under specific reaction conditions. Directly functional! Cyanation and olefination was accomplished in one pot from benzoyl azides through an unprecedented directing group transformation. The method generates benzonitriles and can be used for the synthesis of 2-alkenylated benzonitrile derivatives (see scheme).

Ruthenium(ii)-catalyzed C-H activation/C-N bond formation via in situ generated iminophosphorane as the directing group: Construction of annulated pyridin-2(1H)-ones

We describe an efficient and straightforward synthesis of annulated pyridin-2(1H)-ones following condensation of acyl azides with internal alkynes via the ruthenium-catalyzed ortho C-H bond activation. The reaction in DCE proceeds via in situ generation of iminophosphoranes as directing group-coordination of Ru with N-atom-ortho cyclometallation-insertion of an alkyne into the Ru-C bond-protonation-reductive elimination in a domino sequence. The role and stability of in situ generated iminophosphorane and ruling out the possibility for the benzamide involvement was established using 1H and 31P NMR experiments. This journal is

Synthesis and characterisation of isomeric cycloaurated complexes derived from the iminophosphorane Ph3P{double bond, long}NC(O)Ph

Using different organomercury substrates, two isomeric cycloaurated complexes derived from the stabilised iminophosphorane Ph3P{double bond, long}NC(O)Ph were prepared. Reaction of Ph3P{double bond, long}NC(O)Ph with PhCH2

Synthesis, structure, and reactivity of N -benzoyl iminophosphoranes ortho lithiated at the benzoyl group

Ortho lithiation of N-benzamido-P,P,P-triaryliminophosphoranes through deprotonation with alkyllithium bases was achieved with ortho-C=O and ortho-P=N chemoselectivity. However, the synthetic scope of these processes was rather limited. Ortho-lithiated N-benzamido-P,P,P-triphenyliminophosphorane 8 was efficiently prepared via lithium/halogen exchange of the corresponding ortho-brominated precursor with s-BuLi in THF at -90 °C. The reaction of 8 with a variety of electrophiles provides an easy and mild method for the regioselective synthesis of ortho-modified iminophosphoranes via C- (alkylation and hydroxyalkylation) and C-X (X = I, Si, P, Sn, and Hg) bond-forming reactions. NMR characterization of 8 in THF solution showed that 8 exists as an equilibrium mixture of one monomer and two dimers. The Li atoms of these species become members of five-membered rings through chelation by the ortho-metalated carbon and the carbonyl oxygen. The dimers differ in the relative orientation of the two chelates with respect to the plane defined by the C2Li 2 core. The equilibrium between all species is established by splitting the dimers into monomers and subsequent recombination with formation of a different dimer.