60472-20-0

Basic information

• Product Name: 5-(4-METHOXYPHENYL)-1H-IMIDAZOL-2-AMINE
• Synonyms: 5-(4-METHOXYPHENYL)-1H-IMIDAZOL-2-AMINE;5-(4-methoxyphenyl)-1H-imidazol-2-amine(SALTDATA: FREE)
• CAS NO: 60472-20-0
• Molecular Formula: C₁₀H₁₁N₃O
• Molecular Weight: 189.21
• Mol File: 60472-20-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 447.9°C at 760 mmHg
• Flash Point: 224.7°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 3.25E-08mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 5-(4-METHOXYPHENYL)-1H-IMIDAZOL-2-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-METHOXYPHENYL)-1H-IMIDAZOL-2-AMINE(60472-20-0)
• EPA Substance Registry System: 5-(4-METHOXYPHENYL)-1H-IMIDAZOL-2-AMINE(60472-20-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 60472-20-0(Hazardous Substances Data)

Usage

General Description

5-(4-Methoxyphenyl)-1H-imidazol-2-amine is a chemical compound with the molecular formula C10H11N3O. 5-(4-METHOXYPHENYL)-1H-IMIDAZOL-2-AMINE is an imidazole derivative, which is a class of organic compounds containing a five-membered ring with two nitrogen atoms. It is known to have potential pharmaceutical applications, particularly as an antifungal agent. The 4-methoxyphenyl group attached to the imidazole ring is likely to influence its biological activity, as methoxy groups can affect the lipophilicity and receptor binding of a molecule. As an amine, this compound contains a basic nitrogen atom, which could interact with biological targets such as enzymes or receptors. Further research is needed to fully understand the properties and potential uses of 5-(4-Methoxyphenyl)-1H-imidazol-2-amine.

InChI:InChI=1/C10H11N3O/c1-14-8-4-2-7(3-5-8)9-6-12-10(11)13-9/h2-6H,1H3,(H3,11,12,13)

Upstream product

• 119-61-9 benzophenone 
• 113-00-8 guanidine nitrate 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 5699-40-1 monoacetylguanidine 
• 31555-35-8 2-(p-methoxyphenyl)imidazo[1,2-a]pyrimidine 

Downstream Products

• 76507-35-2 5-Bromo-4-(4-methoxy-phenyl)-1H-imidazol-2-ylamine 
• 1449518-30-2 C₂₇H₂₉N₃O₅ 
• 1449518-29-9 2-((2-amino-5-(4-methoxyphenyl)-1H-imidazol-4-yl)(phenyl)methyl)-3-hydroxy-5,5-dimethylcyclohex-2-enone 
• 1449518-28-8 2-((2-amino-5-(4-methoxyphenyl)-1H-imidazol-4-yl)(4-bromophenyl)methyl)-3-hydroxy-5,5-dimethylcyclohex-2-enone 
• 1449518-27-7 2-((2-amino-5-(4-methoxyphenyl)-1H-imidazol-4-yl)(4-chlorophenyl)methyl)-3-hydroxy-5,5-dimethylcyclohex-2-enone 
• 1449518-26-6 2-((2-amino-5-(4-methoxyphenyl)-1H-imidazol-4-yl)(4-methoxyphenyl)methyl)-3-hydroxy-5,5-dimethylcyclohex-2-enone 

Relevant articles and documents

Fragment-Based Approach to Targeting Inosine-5′-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis

Tuberculosis (TB) remains a major cause of mortality worldwide, and improved treatments are needed to combat emergence of drug resistance. Inosine 5′-monophosphate dehydrogenase (IMPDH), a crucial enzyme required for de novo synthesis of guanine nucleotid

Synthesis, antimicrobial, and anti-inflammatory activities of acetamido pyrrolyl azoles

The acetamido pyrrolyl oxazoles/thiazoles/imidazoles were prepared and tested for their antimicrobial and anti-inflammatory activities. The nitro substituted acetamido pyrrolyl thiazole (11f) and pyrrolyl imidazole (12f) exhibited promising antibacterial activity against K. pneumoniae. The compound 12f showed good antifungal activity against P. chrysogenum. The methoxy acetamido pyrrolyl oxazole (10c) displayed potential anti-inflammatory activity.

COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS

This invention relates to substituted 2-aminoimidazoles and their imidazo[1,2- a]pyrimidinium salts precursors being active against biofilm formation. The present invention also relates to antimicrobial compositions comprising a microbial biofilm formatio