60508-85-2

Basic information

• Product Name: methyl (2,5-dihydroxyphenyl)acetate
• Synonyms: methyl (2,5-dihydroxyphenyl)acetate
• CAS NO: 60508-85-2
• Molecular Weight: 182.176
• Mol File: 60508-85-2.mol

Chemical Properties

• CAS DataBase Reference: methyl (2,5-dihydroxyphenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2,5-dihydroxyphenyl)acetate(60508-85-2)
• EPA Substance Registry System: methyl (2,5-dihydroxyphenyl)acetate(60508-85-2)

Safety Data

• Hazardous Substances Data: 60508-85-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 118555-82-1 2-O-β-D-glucopyranosyloxy-5-hydroxyphenylacetic acid 
• 106-51-4 p-benzoquinone 
• 1084-96-4 2,5-bis(acetyloxy)benzoic acid 
• 860183-06-8 2-ethoxy-benzofuran-5-ol 
• 37785-02-7 2,5-diacetoxybenzoyl chloride 
• 2688-48-4 5-Hydroxy-2-coumaranone 
• 451-13-8 homogentisic acid 
• 408336-37-8 (2,5-diacetoxy-phenyl)-acetic acid methyl ester 
• 186581-53-3 diazomethane 

Downstream Products

• 1290605-69-4 methyl 2-[2,5-bis(pyridinylmethoxy)phenyl]acetate 
• 225650-64-6 p-nitrophenyl 2,5-dihydroxyphenylacetate bis-tetrahydropyranyl ester 
• 225650-68-0 2,5-dihydroxyphenylacetic acid bis-tetrahydropyranyl ester 
• 112450-23-4 (3,6-Dioxo-cyclohexa-1,4-dienyl)-acetic acid methyl ester 
• 6202-39-7 homogentisic acid methyl ester dimethyl ether 
• 441356-57-6 methyl 2-(2-hydroxy-3-methoxyphenyl)acetate 

Relevant articles and documents

PHASEOLOIDIN, A HOMOGENTISIC ACID GLUCOSIDE FROM ENTADA PHASEOLOIDES

The structure of phaseoloidine isolated from the seeds of Entada phaseolides has been determined as homogentisic acid 2-O-β-D-glucopyranoside by chemical and spectral means.

DITHIAZOLE COMPOUNDS, MATRIX METALLOPROTEASE INHIBITORS AND EXTERNAL PREPARATIONS FOR THE SKIN

A dithiazole compound or a salt thereof expressed by formula (I): wherein R1, is hydrogen atom, alkyl, etc.; R2 is hydrogen atom, hydroxy, alkyl, aryl, arylalkoxy, arylalkyl, etc.; R3 is one group of formulae (II), (III) and (IV): This compound has an excellent inhibiting action on matrix metalloprotease (MMPs) activity, and is useful for pharmaceutical, cosmetic and skin external compositions.

Hydroquinone-based derivatization reagents for the quantitation of amines using electrochemical detection

Two new reagents, NDTE (2,5-dihydroxyphenylacetic acid, 2,5-bis-tetrahydropyranyl etherp-nitrophenyl ester) and HLTE (homogentisic γ-lactone tetrahydropyranyl ether), are described for the chemical derivatization of primary and/or secondary amines to form an electrochemically active product. These reagents undergo reaction with the aforementioned analytes to form a product possessing the hydroquinone moiety, thus allowing for reversible electrochemical detection at mild oxidation potentials. The reactivity of each reagent was demonstrated by using N-ethylbenzylamine (EBzA) and the dipeptide isoleucine leucine methyl ester as model analytes. The investigation included the isolation and identification of the intermediates and final products from derivatization of EBzA. These isolated standards were subsequently characterized with respect to electrochemical properties by means of cyclic voltammetry. In LC-EC experiments, the concentration limit of detection (CLOD) of the purified EBzA product was determined to be 5 nM (100 fmol) at a detection potential of +200 mV vs Ag/AgCl ([Cl-] = 3 M). The CLOD values obtained by LC-EC after derivatization of aqueous solutions of EBzA and Ile-Leu-OMe with NDTE were 25 nM (250 fmol) and 250 nM (2.5 pmol), respectively.