60510-53-4

Basic information

• Product Name: 2-(3-phenyl-1,2-oxazol-5-yl)benzoic acid
• CAS NO: 60510-53-4
• Molecular Formula: C₁₆H₁₁NO₃
• Molecular Weight: 265.2634
• Mol File: 60510-53-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 471.9°C at 760 mmHg
• Flash Point: 239.2°C
• Density: 1.271g/cm³
• Vapor Pressure: 1.04E-09mmHg at 25°C
• Refractive Index: 1.614
• CAS DataBase Reference: 2-(3-phenyl-1,2-oxazol-5-yl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-phenyl-1,2-oxazol-5-yl)benzoic acid(60510-53-4)
• EPA Substance Registry System: 2-(3-phenyl-1,2-oxazol-5-yl)benzoic acid(60510-53-4)

Safety Data

• Hazardous Substances Data: 60510-53-4(Hazardous Substances Data)

Upstream product

• 61001-54-5 2-methyldibenzoylmethane 
• 64692-99-5 Sodium salt of 2-carboxybenzaldehyde 
• 27326-43-8 2-vinylbenzoic acid 
• 69810-71-5 Methyl 2-(3-phenyl-2-isoxazolin-5-yl)benzoate 
• 83727-25-7 Methyl 2-<3-phenyl-2-isoxazol-5-yl>benzoate 
• 42222-79-7 1-(2-Carboxyphenyl)-3-phenylpropan-1,3-dione 
• 13203-89-9 3-phenacylphthalide 
• 65349-18-0 3-(1-bromo-2-oxo-2-phenyl-ethyl)-3H-isobenzofuran-1-one 
• 65349-21-5 5-(2′-methylphenyl)-3-phenylisoxazole 
• 28269-50-3 2-vinylbenzoic acid chloride 
• 27326-44-9 methyl o-vinylbenzoate 

Relevant articles and documents

Nitrile Oxide Cycloaddtion Routes to 2-(Isoxazolyl)benzoates and 2-(1,2,4-Oxadiazol-3-yl)benzoates

Cycloaddition of aromatic nitrile oxides to methyl o-vinylbenzoate produced methyl 2-(3-aryl-2-isoxazolin-5-yl)benzoates; the isoxazolines were converted to methyl 2-(3-arylisoxazol-5-yl)benzoates.Reaction of the nitrile oxide from o-methoxycarbonylbenzohydroximinoyl chloride (11) with phenylacetylene, styrenes, and aromatic nitriles resulted in methyl 2-(5-phenylisoxazol-3-yl)benzoate, methyl 2-(5-aryl-2-isoxazolin-3-yl)benzoates (15) and methyl 2-(5-aryl-1,2,4-oxadiazol-3-yl)benzoates, respectively.The isoxazolines 15 were converted to the corresponding isoxazoles 16.

Isoxazolyl benzoic acids

Substituted or unsubstituted isoxazolyl benzoic acids, e.g. o-(4-methyl-3-phenylisoxazol-5-yl)benzoic acid, are prepared by dehydrating a corresponding 5-hydroxy-2-isoxazolin-5-yl benzoic acid, and are useful as hypolipidemic agents.