6052-79-5

Upstream product

• 90-02-8 salicylaldehyde 
• 504-63-2 trimethyleneglycol 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 118203-14-8 2-(2-Methoxymethoxy-phenyl)-[1,3]dioxane 
• 945656-70-2 C₁₄H₁₉NO₅ 
• 392315-11-6 2-(2-oxopropoxy)benzaldehyde 
• 945656-60-0 2-(2-oxo-2-phenylethoxy)benzaldehyde 
• 93011-70-2 2-(2-oxo-3-phenylpropoxy)benzaldehyde 
• 167165-59-5 3-diphenylphosphino-2-hydroxybenzaldehyde 
• 185019-67-4 (3-[1,3]Dioxan-2-yl-2-methoxymethoxy-phenyl)-diphenyl-phosphane 
• 67868-82-0 2-hydroxy-3-methylthiobenzaldehyde 
• 1234565-67-3 3-methylsulfanyl-5-nitro-salicylic aldehyde 
• 330976-85-7 C₆₀H₅₆O₁₄P₂ 

Relevant academic research and scientific papers

Mustard Carbonate Analogues as Sustainable Reagents for the Aminoalkylation of Phenols

N,N-dialkyl ethylamine moiety can be found in numerous scaffolds of macromolecules, catalysts, and especially pharmaceuticals. Common synthetic procedures for its incorporation in a substrate relies on the use of a nitrogen mustard gas or on multistep syntheses featuring chlorine hazardous/toxic chemistry. Reported herein is a one-pot synthetic approach for the easy introduction of aminoalkyl chain into different phenolic substrates through dialkyl carbonate (β-aminocarbonate) chemistry. This new direct alcohol substitution avoids the use of chlorine chemistry, and it is efficient on numerous pharmacophore scaffolds with good to quantitative yield. The cytotoxicity via MTT of the β-aminocarbonate, key intermediate of this synthetic approach, was also evaluated and compared with its alcohol precursor.

Mesoporous poly-melamine-formaldehyde (mPMF)-a highly efficient catalyst for chemoselective acetalization of aldehydes

A mesoporous poly-melamine-formaldehyde polymer with a high surface area, good porosity and a high density of amine and triazine functional groups was investigated as a highly efficient hydrogen-bonding catalyst. This porous organic polymer was found to be highly effective in catalyzing chemoselective acetalization of aldehydes, without the consumption of any dehydrating agents. The turnover frequency of mesoporous poly-melamine-formaldehyde is hundreds of times higher than melamine monomer, and this high efficiency is due to the high density of aminal (-NH-CH2-NH-) groups and triazine rings in the polymer network, which provides an inherently powerful system with multiple hydrogen bonds. This unique characteristic imparts mesoporous poly-melamine-formaldehyde polymer with a very high activity as a heterogeneous organocatalyst. The polymer is also low cost, and easy to be synthesized and recycled.

A METHOD OF ACETALIZING AN ALDEHYDE

A method of acetalizing an aldehyde comprising reacting said aldehyde with an alcohol in the presence of a polymeric catalyst to form an acetal wherein the polymeric catalyst is a mesoporous poly-melamine-formaldehyde polymer.

TIME TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS

The present invention relates to photochromic spiropyrans as active ingredients of Time-Temperature Indicators (TTIs), and to new spiropyrans per se. More particularly, the invention provides TTIs on the base of photochromic spiropyrans comprising alkylsu

Tetrabutylammonium tribromide (TBATB) as an efficient generator of HBr for an efficient chemoselective reagent for acetalization of carbonyl compounds

Acyclic and cyclic acetals of various carbonyl compounds were obtained in excellent yields under a mild reaction condition in the presence of trialkyl orthoformate and a catalytic amount of tetrabutylammonium tribromide (TBATB) in absolute alcohol. Chemoselective acetalization of an aldehyde in the presence of ketone, unsymmetrical acetal formation, shorter reaction times, mild reaction conditions, the stability of acid-sensitive protecting groups, high efficiencies, facile isolation of the desired products, and the catalytic nature of the reagent make the present methodology a practical alternative.

Luminol-dependent photoemission from macrophages stimulated by cyclic acetals of salicylaldehyde

The synthesis and structure of several cyclic acetals of 2-hydroxybenzaldehyde (salicylaldehyde) and various 1,2-or 1,3-diols are described. These compounds were tested as the enhancers or inhibitors of luminol-dependent chemiluminescence of macrophages.

The first chiral early-late heterobimetallic complex - A titanium(IV)-palladium(II) complex based on salenophos

The synthesis of the chiral polyfunctional diphosphine salenophos 1 is described. The new ligand bearing hard and soft coordination sites chelates titanium(IV) as well as palladium(II) in a defined manner provided a certain order during the introduction of the two metals was kept. In this way the first chiral early-late heterobimetallic complex could be synthesized. It was fully characterized by NMR spectroscopy and X-ray structural analysis. Remarkable features of the heterobimetallic complex are the trans coordination of the phosphine groups on palladium and the distance between Ti and Pd which is more than 4.13 A.